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Query: AARS2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
AARS2 1 2.020 0.260 -0.340 0.033 0.625 -0.534 1.513 0.383

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence

Background Information for AARS2:





Protein-protein Interactions for AARS2

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait RAP1B Cat. description Hein, Mann, Cell 2015
Category members IP bait APP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C17orf90 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CD70 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EPHA1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FGL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IL1R2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NDUFS7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RBM3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SCGB1D1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SUCLG1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TRMT1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in AARS2

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Ala-tRNA-synth_IIc_N IPR018164 0.29
Category members Ala-tRNA-synth_IIc_core IPR018165 0.29
Category members tRNA_SAD IPR012947 0.23
Category members Ala-tRNA-lgiase_IIc IPR002318 0.18
Category members Ala-tRNA-ligase_IIc_anticod-bd IPR018162 0.18
Category members Thr/Ala-tRNA-synth_IIc_edit IPR018163 0.08


Protein complexes (CORUM database) featuring AARS2

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring AARS2

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0010467 gene expression Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0000166 nucleotide binding Database 5.91
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members Pathway Pathway_202 REACTOME_TRNA_AMINOACYLATION 0 1.34
Category members GO Category GO:0006418 tRNA aminoacylation for protein translation Database 0.91
Category members GO Category GO:0003676 nucleic acid binding Database 0.83
Category members Pathway Pathway_409 KEGG_AMINOACYL_TRNA_BIOSYNTHESIS 0 0.82
Category members GO Category GO:0016876 ligase activity, forming aminoacyl-tRNA and related compounds Database 0.42
Category members GO Category GO:0004813 alanine-tRNA ligase activity Database 0.29
Category members GO Category GO:0006419 alanyl-tRNA aminoacylation Database 0.29
Category members GO Category GO:0033108 mitochondrial respiratory chain complex assembly Database 0.18
Category members Pathway Pathway_203 REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION 0 0
Category members GO Category GO:0000049 tRNA binding Database 0
Category members GO Category GO:0043039 tRNA aminoacylation Database 0
Category members GO Category GO:0046872 metal ion binding Database 0


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