Results for the Category
REACTOME_IL_7_SIGNALING
(Pathway_1177)
| RNAi screen result | RNAPII IP (MG132) | CSB IP | CSB IP (MG132) | Chrom. | Chrom. (MG132) | Ubi /Phospo | Ubi /Phospho (MG132) |
| W | |||||||
| Gene name | MGoogle Score | RNAi high | RNAi low | RNAPII-IP (MG132) | CSB-IP | CSB-IP (MG132) | Chrom. | Chrom. (MG132) |
|---|---|---|---|---|---|---|---|---|
| PIK3R2 | 1 | 2.740 | -1.180 | 0.269 | 0.348 | |||
| PIK3R3 | 0 | -0.140 | -0.480 | |||||
| PIK3R3 | 0 | -0.140 | -0.480 | -0.441 | 0.147 | |||
| PIK3R1 | 0 | 1.910 | -1.220 | -0.441 | 0.147 | |||
| JAK1 | 0 | 0.190 | -0.100 | -1.504 | -0.381 | -0.438 | ||
| STAT5B | 0 | 0.670 | -0.960 |
| Gene name | PTM type | PTM site | UV | UV (MG132) | Sequence |
|---|---|---|---|---|---|
| JAK1 | Ubiquitylation | K227 | -0.405 | _YIPETLNK(gl)SIR_ | |
| JAK1 | Ubiquitylation | K249 | 0.116 | 0.771 | _DFLK(gl)EFNNK_ |
| JAK1 | Ubiquitylation | K559 | -0.478 | _EISNLLVATK(gl)K_ | |
| PIK3R2 | Phosphorylation | S262 | -2.237 | _APPPPS(ph)SPPPGGAPDGSEPSPDFPALLVEK_ | |
| PIK3R2 | Phosphorylation | S263 | -2.237 | _APPPPS(ph)SPPPGGAPDGSEPSPDFPALLVEK_ | |
| PIK3R2 | Ubiquitylation | K500 | -0.189 | _IFEEQGQTQEK(gl)CSK_ | |
| PIK3R2 | Ubiquitylation | K541 | -0.609 | _TK(gl)LEQQLR_ | |
| PIK3R2 | Ubiquitylation | K564 | -0.431 | -1.022 | _MNSLK(gl)PDLMQLR_ |
| PIK3R3 | Ubiquitylation | K226 | -0.376 | _YQQDQLVKEDNIDAVGKK(gl)_ | |
| PIK3R3 | Ubiquitylation | K320 | 0.385 | _LGEIHDSK(gl)MR_ | |
| STAT5B | Phosphorylation | S194 | 0.270 | _IQAQFGPLAQLS(ph)PQER_ |
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