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Leber congenital amaurosis
(Leber_congenital_amaurosis)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
W

Protein Results:

Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
IMPDH1 2 -0.140 -0.120 0.626 0.542
CEP290 1 1.020 -0.690
CEP290 1 2.010 -1.090
IQCB1 0 0.882
NMNAT1 0 -1.410 1.630

PTM Sites:

Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
CEP290 Ubiquitylation K593 -1.125 _K(gl)LDLLSLK_
CEP290 Ubiquitylation K735 -1.199 _KEAINYSQQLAK(gl)ANLK_
CEP290 Ubiquitylation K830 0.626 _EYLSEK(gl)ETWK_
CEP290 Ubiquitylation K1178 -1.408 _DK(gl)EVESLR_
CEP290 Ubiquitylation K1336 -0.794 _GLEELISTLK(gl)DTK_
CEP290 Ubiquitylation K1552 -0.135 _LNQK(gl)EEVLKK_
CEP290 Ubiquitylation K1682 0.578 _LQLQENHEDEVKK(gl)_
IMPDH1 Phosphorylation T6 -0.746 -1.087 _(ac)M(ox)EGPLT(ph)PPPLQGGGAAAVPEPGAR_
IMPDH1 Ubiquitylation K293 0.154 0.299 _GK(gl)LPIVNDCDELVAIIAR_
IMPDH1 Ubiquitylation K327 2.285 1.616 _DSQK(gl)QLLCGAAVGTR_
IMPDH1 Ubiquitylation K507 0.433 _GMGSLDAMEK(gl)SSSSQKR_
IMPDH1 Ubiquitylation K523 0.629 _YFSEGDKVK(gl)_
IMPDH1 Ubiquitylation K535 0.179 -0.096 _IAQGVSGSIQDK(gl)GSIQK_
NMNAT1 Phosphorylation S117 0.826 1.209 _LEASDCDHQQNS(ph)PTLERPGR_


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