Results for the Category
Juvenile amyotrophic lateral sclerosis
(Juvenile_amyotrophic_lateral_sclerosis)
| RNAi screen result | RNAPII IP (MG132) | CSB IP | CSB IP (MG132) | Chrom. | Chrom. (MG132) | Ubi /Phospo | Ubi /Phospho (MG132) |
| W | |||||||
| Gene name | MGoogle Score | RNAi high | RNAi low | RNAPII-IP (MG132) | CSB-IP | CSB-IP (MG132) | Chrom. | Chrom. (MG132) |
|---|---|---|---|---|---|---|---|---|
| SIGMAR1 | 1 | 4.327 | ||||||
| ALS2 | 0 | -0.780 | 1.190 | |||||
| FUS | 0 | -0.360 | 0.760 | -0.267 | -1.116 | 0.302 | ||
| SPG11 | 0 | 1.830 | -1.010 |
| Gene name | PTM type | PTM site | UV | UV (MG132) | Sequence |
|---|---|---|---|---|---|
| ALS2 | Phosphorylation | S466 | 1.095 | 0.857 | _KSSS(ph)LVDIREEETEGGSR_ |
| ALS2 | Phosphorylation | S492 | 0.013 | 0.308 | _LSLPGLLSQVS(ph)PR_ |
| ALS2 | Phosphorylation | S1462 | -0.133 | -0.364 | _S(ph)ESPEPGYVVTSSGLLLPVLLPR_ |
| ALS2 | Phosphorylation | S1464 | -0.535 | -0.600 | _SES(ph)PEPGYVVTSSGLLLPVLLPR_ |
| FUS | Ubiquitylation | K319 | 0.572 | _K(gl)TGQPMINLYTDR_ | |
| SPG11 | Ubiquitylation | K353 | -1.074 | _AQLSSLNETIKNSK(gl)_ | |
| SPG11 | Ubiquitylation | K552 | -1.385 | _SK(gl)ENLFNPSSK_ | |
| SPG11 | Ubiquitylation | K981 | -0.707 | _IGGVIQDTLPVQNYK(gl)TK_ | |
| SPG11 | Ubiquitylation | K1300 | -0.516 | _ESVAEK(gl)LSK_ | |
| SPG11 | Ubiquitylation | K1724 | -1.234 | _HIEQWSLK(gl)QAR_ | |
| SPG11 | Ubiquitylation | K2208 | 0.052 | _TALLDYIK(gl)R_ |
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