Results for the Category
positive regulation of T cell receptor signaling pathway
(GO:0050862)
| RNAi screen result | RNAPII IP (MG132) | CSB IP | CSB IP (MG132) | Chrom. | Chrom. (MG132) | Ubi /Phospo | Ubi /Phospho (MG132) |
| W | |||||||
| Gene name | MGoogle Score | RNAi high | RNAi low | RNAPII-IP (MG132) | CSB-IP | CSB-IP (MG132) | Chrom. | Chrom. (MG132) |
|---|---|---|---|---|---|---|---|---|
| PRKD2 | 0 | 0.050 | 0.170 | 0.914 | ||||
| PRKD2 | 0 | 0.050 | 0.170 | |||||
| LCK | 0 | -0.490 | 1.390 | 0.295 | 0.576 | |||
| ADA | 0 | 0.340 | -0.830 |
| Gene name | PTM type | PTM site | UV | UV (MG132) | Sequence |
|---|---|---|---|---|---|
| ADA | Ubiquitylation | K312 | 0.123 | _STLDTDYQMTK(gl)R_ | |
| LCK | Phosphorylation | T37 | -0.435 | _YRPENTPEPVSTSVSHYGAEPT(ph)TVSPCPSSSAK_ | |
| LCK | Ubiquitylation | K191 | -0.112 | 0.264 | _ESETTK(gl)GAYSLSIR_ |
| LCK | Ubiquitylation | K235 | 0.323 | _AQFDTLQK(gl)LVK_ | |
| LCK | Ubiquitylation | K259 | -1.613 | _LTTVCPTVK(gl)PQTQGLAK_ | |
| PRKD2 | Phosphorylation | S197 | 0.239 | 0.895 | _RLS(ph)STSLASGHSVR_ |
| PRKD2 | Phosphorylation | T211 | -0.119 | _LGT(ph)SESLPCTAEELSR_ | |
| PRKD2 | Phosphorylation | S212 | 0.113 | _LGTS(ph)ESLPCTAEELSR_ | |
| PRKD2 | Phosphorylation | S214 | 0.216 | 0.302 | _LGTSES(ph)LPCTAEELSR_ |
| PRKD2 | Phosphorylation | S710 | -0.413 | -0.511 | _S(ph)VVGTPAYLAPEVLLNQGYNR_ |
| PRKD2 | Phosphorylation | T714 | -0.279 | _S(ph)VVGTPAYLAPEVLLNQGYNR_ | |
| PRKD2 | Ubiquitylation | K730 | 1.177 | _IIGEK(gl)SFR_ | |
| PRKD2 | Phosphorylation | S886 | -0.718 | -0.305 | _DLGGACPPQDHDMQGLAERIS(ph)VL_ |
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