Results for the Category
negative regulation of osteoclast differentiation
(GO:0045671)
| RNAi screen result | RNAPII IP (MG132) | CSB IP | CSB IP (MG132) | Chrom. | Chrom. (MG132) | Ubi /Phospo | Ubi /Phospho (MG132) |
| W | |||||||
| Gene name | MGoogle Score | RNAi high | RNAi low | RNAPII-IP (MG132) | CSB-IP | CSB-IP (MG132) | Chrom. | Chrom. (MG132) |
|---|---|---|---|---|---|---|---|---|
| PIK3R1 | 0 | 1.910 | -1.220 | -0.441 | 0.147 | |||
| CTNNB1 | 0 | 0.490 | -0.230 | |||||
| CTNNB1 | 0 | 0.490 | -0.230 | -0.415 | 0.628 | 0.215 | ||
| NF1 | 0 | 1.000 | -0.500 | 0.444 | -0.190 |
| Gene name | PTM type | PTM site | UV | UV (MG132) | Sequence |
|---|---|---|---|---|---|
| CTNNB1 | Ubiquitylation | K158 | -1.265 | _AIPELTK(gl)LLNDEDQVVVNK_ | |
| CTNNB1 | Ubiquitylation | K180 | -0.546 | -0.636 | _AAVM(ox)VHQLSK(gl)K_ |
| CTNNB1 | Ubiquitylation | K181 | -0.717 | -0.729 | _AAVMVHQLSKK(gl)_ |
| CTNNB1 | Phosphorylation | S191 | -0.024 | 0.129 | _S(ph)PQMVSAIVR_ |
| CTNNB1 | Ubiquitylation | K435 | -0.350 | _NK(gl)MM(ox)VCQVGGIEALVR_ | |
| CTNNB1 | Ubiquitylation | K496 | -1.262 | _LHYGLPVVVK(gl)_ | |
| CTNNB1 | Phosphorylation | S552 | 1.233 | 1.224 | _RTS(ph)MGGTQQQFVEGVR_ |
| CTNNB1 | Phosphorylation | T556 | 1.275 | 0.995 | _RTSM(ox)GGT(ph)QQQFVEGVR_ |
| CTNNB1 | Ubiquitylation | K671 | -0.941 | -0.934 | _MSEDKPQDYK(gl)K_ |
| NF1 | Ubiquitylation | K471 | 0.218 | _MAPSLTFKEK(gl)_ | |
| NF1 | Phosphorylation | S864 | -0.458 | _SNSGLATYS(ph)PPMGPVSER_ | |
| NF1 | Phosphorylation | T2514 | 0.076 | _GSEGYLAATYPTVGQT(ph)SPR_ | |
| NF1 | Phosphorylation | S2515 | 0.071 | 0.316 | _GSEGYLAATYPTVGQTS(ph)PR_ |
| NF1 | Phosphorylation | S2543 | 0.698 | 0.655 | _S(ph)FDHLISDTK_ |
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