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Results for the Category
regulation of endodeoxyribonuclease activity
(GO:0032071)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
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Protein Results:

 Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
NPM1 1 1.010 -0.750 0.063 -0.066 -0.259
SIRT1 0 0.910 -0.910

PTM Sites:

 Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
NPM1 Phosphorylation S4 -0.102 0.205 _(ac)MEDS(ph)MDMDMSPLRPQNYLFGCELK_
NPM1 Phosphorylation S10 0.493 0.606 _(ac)MEDSMDM(ox)DM(ox)S(ph)PLRPQNYLFGCELK_
NPM1 Phosphorylation Y67 0.604 0.383 _TVSLGAGAKDELHIVEAEAMNY(ph)EGSPIKVTLATLK_
NPM1 Phosphorylation S70 0.285 0.333 _TVSLGAGAKDELHIVEAEAMNYEGS(ph)PIK_
NPM1 Phosphorylation T75 0.611 0.229 _DELHIVEAEAMNYEGSPIKVT(ph)LATLK_
NPM1 Phosphorylation T78 0.397 _TVSLGAGAKDELHIVEAEAMNYEGSPIKVTLAT(ph)LK_
NPM1 Phosphorylation S125 0.202 0.017 _CGSGPVHISGQHLVAVEEDAES(ph)EDEEEEDVK_
NPM1 Phosphorylation S139 -0.611 _LLSIS(ph)GKR_
NPM1 Ubiquitylation K141 0.568 1.699 _LLSISGK(gl)R_
NPM1 Ubiquitylation K150 -1.308 0.669 _SAPGGGSK(gl)VPQKK_
NPM1 Ubiquitylation K202 0.335 0.204 _SIRDTPAK(gl)NAQK_
NPM1 Phosphorylation S227 0.788 _SKGQES(ph)FKK_
NPM1 Phosphorylation S243 -0.070 0.063 _GPSS(ph)VEDIK_
NPM1 Ubiquitylation K248 0.294 1.847 _GPSSVEDIK(gl)AK_
NPM1 Ubiquitylation K250 0.931 1.267 _AK(gl)MQASIEK_
NPM1 Phosphorylation S254 -0.677 0.371 _MQAS(ph)IEK_
NPM1 Ubiquitylation K257 0.236 0.753 _MQASIEK(gl)GGSLPK_
NPM1 Phosphorylation S260 -0.202 0.203 _GGS(ph)LPKVEAK_
NPM1 Ubiquitylation K267 0.954 1.794 _VEAK(gl)FINYVK_
SIRT1 Phosphorylation S14 -0.369 -0.246 _(ac)ADEAALALQPGGS(ph)PSAAGADR_
SIRT1 Phosphorylation S16 -0.306 -1.665 _(ac)ADEAALALQPGGS(ph)PS(ph)AAGADREAASSPAGEPLR_
SIRT1 Phosphorylation S26 -1.047 -0.245 _EAAS(ph)SPAGEPLR_
SIRT1 Phosphorylation S27 0.351 -0.363 _EAASS(ph)PAGEPLR_
SIRT1 Phosphorylation S47 -0.574 -0.607 _S(ph)PGEPGGAAPER_
SIRT1 Ubiquitylation K238 -1.641 _RK(gl)DINTIEDAVK_
SIRT1 Ubiquitylation K499 -2.138 -0.204 _LGGEYAK(gl)LCCNPVK_
SIRT1 Ubiquitylation K578 -2.782 _GCMEEK(gl)PQEVQTSR_
SIRT1 Ubiquitylation K601 -3.051 _NVESIAEQMENPDLK(gl)NVGSSTGEK_


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