Results for the Category
nuclear exosome (RNase complex)
(GO:0000176)
| RNAi screen result | RNAPII IP (MG132) | CSB IP | CSB IP (MG132) | Chrom. | Chrom. (MG132) | Ubi /Phospo | Ubi /Phospho (MG132) |
| W | |||||||
| Gene name | MGoogle Score | RNAi high | RNAi low | RNAPII-IP (MG132) | CSB-IP | CSB-IP (MG132) | Chrom. | Chrom. (MG132) |
|---|---|---|---|---|---|---|---|---|
| EXOSC3 | 1 | -1.840 | 3.020 | -0.152 | -0.472 | -0.227 | -0.542 | -0.121 |
| DIS3 | 0 | 0.150 | -0.690 | |||||
| DIS3 | 0 | 0.150 | -0.690 | -0.335 | -0.438 | -0.111 | ||
| EXOSC9 | 0 | 0.080 | 0.519 | 0.128 | -0.495 | 0.107 | ||
| MPHOSPH6 | 0 | -0.590 | 0.210 | -0.494 | 0.236 | |||
| EXOSC10 | 0 | 0.160 | -0.170 | -0.327 | -0.108 | -0.734 | -0.003 |
| Gene name | PTM type | PTM site | UV | UV (MG132) | Sequence |
|---|---|---|---|---|---|
| DIS3 | Ubiquitylation | K337 | -0.491 | _TAVSEK(gl)MLKPTGR_ | |
| DIS3 | Ubiquitylation | K535 | -0.201 | _RGTTVYLCEK(gl)R_ | |
| EXOSC10 | Ubiquitylation | K591 | -1.148 | _SEVAAGVK(gl)K_ | |
| EXOSC10 | Ubiquitylation | K592 | -1.148 | _SEVAAGVK(gl)K_ | |
| EXOSC10 | Ubiquitylation | K680 | -1.926 | _GPLTVAQKK(gl)_ | |
| EXOSC10 | Ubiquitylation | K710 | -1.867 | _APVSQAAK(gl)FDPSTK_ | |
| EXOSC10 | Ubiquitylation | K716 | -2.215 | _FDPSTK(gl)IYEISNR_ | |
| EXOSC9 | Ubiquitylation | K52 | 0.195 | _ISFGTDYGCCIVELGK(gl)TR_ | |
| EXOSC9 | Phosphorylation | S306 | 0.254 | 0.180 | _APIDTS(ph)DVEEK_ |
| MPHOSPH6 | Ubiquitylation | K128 | 0.193 | _RYETLVGTIGKK(gl)_ | |
| MPHOSPH6 | Phosphorylation | T147 | 0.548 | -0.219 | _RDHANYEEDENGDIT(ph)PIK_ |
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