Results for the Category
negative regulation of epidermal growth factor-activated receptor activity
(GO:0007175)
| RNAi screen result | RNAPII IP (MG132) | CSB IP | CSB IP (MG132) | Chrom. | Chrom. (MG132) | Ubi /Phospo | Ubi /Phospho (MG132) |
| W | |||||||
| Gene name | MGoogle Score | RNAi high | RNAi low | RNAPII-IP (MG132) | CSB-IP | CSB-IP (MG132) | Chrom. | Chrom. (MG132) |
|---|---|---|---|---|---|---|---|---|
| PSEN1 | 0 | 0.930 | -1.110 | |||||
| ERRFI1 | 0 | 0.630 | -0.570 | |||||
| SNX6 | 0 | 0.090 | -0.550 | |||||
| ZFYVE28 | 0 | |||||||
| ZGPAT | 0 | 1.020 | -1.070 | 0.249 |
| Gene name | PTM type | PTM site | UV | UV (MG132) | Sequence |
|---|---|---|---|---|---|
| ERRFI1 | Phosphorylation | S251 | -0.455 | _SHS(ph)GPAGSFNKPAIR_ | |
| PSEN1 | Phosphorylation | S313 | 0.844 | _VSKNS(ph)KYNAESTER_ | |
| PSEN1 | Ubiquitylation | K314 | 0.016 | 0.414 | _NSK(gl)YNAESTER_ |
| PSEN1 | Phosphorylation | S366 | -0.340 | 0.055 | _AAVQELSS(ph)SILAGEDPEER_ |
| PSEN1 | Phosphorylation | S367 | 0.005 | 0.066 | _AAVQELSSS(ph)ILAGEDPEER_ |
| SNX6 | Ubiquitylation | K119 | 0.721 | 0.619 | _LGEGEGSMTK(gl)EEFTK_ |
| SNX6 | Ubiquitylation | K291 | 0.222 | _VSADEDLK(gl)LSDLLK_ | |
| SNX6 | Ubiquitylation | K307 | 0.601 | _ESQAAK(gl)DLLYR_ | |
| ZFYVE28 | Ubiquitylation | K87 | -0.163 | -0.341 | _DFCVK(gl)FPEEIR_ |
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