Results for the Category
Autosomal dominant optic atrophy plus syndrome
(Autosomal_dominant_optic_atrophy_plus_syndrome)
RNAi screen result | RNAPII IP (MG132) | CSB IP | CSB IP (MG132) | Chrom. | Chrom. (MG132) | Ubi /Phospo | Ubi /Phospho (MG132) |
W | |||||||
Gene name | MGoogle Score | RNAi high | RNAi low | RNAPII-IP (MG132) | CSB-IP | CSB-IP (MG132) | Chrom. | Chrom. (MG132) |
---|---|---|---|---|---|---|---|---|
MFN2 | 1 | 0.100 | 0.320 | 0.028 | ||||
OPA1 | 0 | -0.940 | 1.320 | 0.057 | -0.292 | |||
OPA1 | 0 | -0.940 | 1.320 | 0.962 | 0.828 | 0.737 |
Gene name | PTM type | PTM site | UV | UV (MG132) | Sequence |
---|---|---|---|---|---|
MFN2 | Ubiquitylation | K84 | 1.579 | 0.761 | _GYLSK(gl)VR_ |
MFN2 | Ubiquitylation | K316 | -0.574 | _IQK(gl)AQGMPEGGGALAEGFQVR_ | |
MFN2 | Ubiquitylation | K357 | 0.235 | -0.035 | _TK(gl)FEQHTVR_ |
MFN2 | Ubiquitylation | K366 | -0.376 | _AK(gl)QIAEAVR_ | |
MFN2 | Ubiquitylation | K416 | -0.150 | 0.279 | _QLELLAQDYK(gl)LR_ |
MFN2 | Ubiquitylation | K420 | 1.342 | 0.355 | _IK(gl)QITEEVER_ |
MFN2 | Ubiquitylation | K463 | -0.905 | _VYK(gl)NELHR_ | |
MFN2 | Ubiquitylation | K560 | -0.434 | _FLGPK(gl)NSRR_ | |
MFN2 | Ubiquitylation | K719 | -0.768 | _ENLEQEIAAMNK(gl)K_ | |
MFN2 | Ubiquitylation | K720 | -0.575 | _ENLEQEIAAMNKK(gl)_ | |
MFN2 | Ubiquitylation | K730 | -1.137 | _KIEVLDSLQSK(gl)AK_ | |
OPA1 | Ubiquitylation | K261 | 0.390 | _AAGQYSTSYAQQK(gl)R_ |
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