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Results for the Category
Autosomal dominant optic atrophy plus syndrome
(Autosomal_dominant_optic_atrophy_plus_syndrome)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
W

Protein Results:

Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
MFN2 1 0.100 0.320 0.028
OPA1 0 -0.940 1.320 0.057 -0.292
OPA1 0 -0.940 1.320 0.962 0.828 0.737

PTM Sites:

Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
MFN2 Ubiquitylation K84 1.579 0.761 _GYLSK(gl)VR_
MFN2 Ubiquitylation K316 -0.574 _IQK(gl)AQGMPEGGGALAEGFQVR_
MFN2 Ubiquitylation K357 0.235 -0.035 _TK(gl)FEQHTVR_
MFN2 Ubiquitylation K366 -0.376 _AK(gl)QIAEAVR_
MFN2 Ubiquitylation K416 -0.150 0.279 _QLELLAQDYK(gl)LR_
MFN2 Ubiquitylation K420 1.342 0.355 _IK(gl)QITEEVER_
MFN2 Ubiquitylation K463 -0.905 _VYK(gl)NELHR_
MFN2 Ubiquitylation K560 -0.434 _FLGPK(gl)NSRR_
MFN2 Ubiquitylation K719 -0.768 _ENLEQEIAAMNK(gl)K_
MFN2 Ubiquitylation K720 -0.575 _ENLEQEIAAMNKK(gl)_
MFN2 Ubiquitylation K730 -1.137 _KIEVLDSLQSK(gl)AK_
OPA1 Ubiquitylation K261 0.390 _AAGQYSTSYAQQK(gl)R_


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