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Query: ZWINT

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ZWINT 0 0.420 1.220 -0.330

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
ZWINT Ubiquitylation K97 -1.008 0.532 _EQWK(gl)ELK_
ZWINT Ubiquitylation K100 -0.527 0.293 _ELK(gl)ATYR_
ZWINT Ubiquitylation K141 -0.371 0.030 _EAFEQLQAK(gl)K_
ZWINT Ubiquitylation K196 -0.112 0.009 _LGNLK(gl)QQAEQER_
ZWINT Ubiquitylation K142 -0.150 _EAFEQLQAKK(gl)_
ZWINT Ubiquitylation K93 -2.211 -0.410 _AIAAK(gl)EQWK_
ZWINT Ubiquitylation K111 -0.138 _EHVEAIK(gl)IGLTK_

Background Information for ZWINT:


Pubmed-ZWINT »
Uniprot-ZWINT »
Biogrid-ZWINT »
ProteomicsDB-ZWINT »

Tumorportal-ZWINT »
COSMIC-ZWINT »
GenomeRNAi-ZWINT »
Genecards-ZWINT


Protein-protein Interactions for ZWINT
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait BUB1 Cat. description Hein, Mann, Cell 2015
Category members IP bait C20orf172;DSN1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CASC5 Cat. description Hein, Mann, Cell 2015
Category members IP bait MIS12 Cat. description Hein, Mann, Cell 2015
Category members IP bait NUF2 Cat. description Hein, Mann, Cell 2015
Category members IP bait SPC24 Cat. description Hein, Mann, Cell 2015
Category members IP bait ZWINT Cat. description Hein, Mann, Cell 2015
Category members IP bait C22orf41 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CCDC22 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EXOC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM167A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LTBR Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MLF1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NEU2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NSL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PCOLCE2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PMF1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait STX11 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait STX19 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait THBS2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZWINT Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in ZWINT
Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring ZWINT
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 1464 Mis12 centromere complex Database 0.08


Categories featuring ZWINT
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Pathway Pathway_320 REACTOME_CELL_CYCLE 0 11.08
Category members GO Category GO:0000278 mitotic cell cycle Database 10.63
Category members Pathway Pathway_321 REACTOME_MITOTIC_M_M_G1_PHASES 0 5.47
Category members Pathway Pathway_323 REACTOME_DNA_REPLICATION 0 5.24
Category members Pathway Pathway_317 REACTOME_CELL_CYCLE_MITOTIC 0 4.82
Category members Pathway Pathway_726 REACTOME_MITOTIC_PROMETAPHASE 0 2.41
Category members GO Category GO:0000776 kinetochore Database 2.24
Category members GO Category GO:0047485 protein N-terminus binding Database 1.84
Category members GO Category GO:0048015 phosphatidylinositol-mediated signaling Database 0.98
Category members GO Category GO:0007049 cell cycle Database 0.69
Category members GO Category GO:0043231 intracellular membrane-bounded organelle Database 0.43
Category members GO Category GO:0000777 condensed chromosome kinetochore Database 0.32
Category members GO Category GO:0007093 mitotic cell cycle checkpoint Database 0.27
Category members GO Category GO:0030425 dendrite Database 0.26
Category members GO Category GO:0043005 neuron projection Database 0.08
Category members GO Category GO:0007051 spindle organization Database 0.04
Category members GO Category GO:0000070 mitotic sister chromatid segregation Database 0
Category members GO Category GO:0051649 establishment of localization in cell Database 0


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