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Query: XPNPEP1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
XPNPEP1 1 0.200 3.440 -1.350

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
XPNPEP1 Ubiquitylation K641 0.601 -0.401 _DVIGK(gl)ELQK_
XPNPEP1 Ubiquitylation K47 0.018 _(ac)M(ox)PPK(gl)VTSELLR_
XPNPEP1 Ubiquitylation K589 -0.200 _IENVVLVVPVK(gl)TK_
XPNPEP1 Ubiquitylation K591 -0.200 _IENVVLVVPVK(gl)TK_

Background Information for XPNPEP1:


Pubmed-XPNPEP1 »
Uniprot-XPNPEP1 »
Biogrid-XPNPEP1 »
ProteomicsDB-XPNPEP1 »

Tumorportal-XPNPEP1 »
COSMIC-XPNPEP1 »
GenomeRNAi-XPNPEP1 »
Genecards-XPNPEP1


Protein-protein Interactions for XPNPEP1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait RAB30 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SPIN2B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WDR4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in XPNPEP1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Creatinase_N IPR000587 0
Category members Pept_M24_structural-domain IPR000994 0
Category members Creatinase/Aminopeptidase_P_N IPR028980 0


Protein complexes (CORUM database) featuring XPNPEP1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring XPNPEP1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0016787 hydrolase activity Database 0.22
Category members GO Category GO:0004177 aminopeptidase activity Database 0.13
Category members GO Category GO:0010815 bradykinin catabolic process Database 0.11
Category members GO Category GO:0006508 proteolysis Database 0
Category members GO Category GO:0030145 manganese ion binding Database 0
Category members GO Category GO:0042803 protein homodimerization activity Database 0
Category members GO Category GO:0046872 metal ion binding Database 0
Category members GO Category GO:0070006 metalloaminopeptidase activity Database 0


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