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Query: WRAP53

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
WRAP53 0 0.400 -0.070 0.260 0.739

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
WRAP53 Phosphorylation T81 -0.102 _EGDPVSLSTPLET(ph)EFGSPSELS(ph)PR_
WRAP53 Phosphorylation T489 -0.148 _VFPEPT(ph)ESGDEGEELGLPLLSTR_
WRAP53 Phosphorylation S87 -0.568 -0.280 _EGDPVSLSTPLETEFGSPS(ph)ELSPR_
WRAP53 Phosphorylation S491 -0.497 -0.539 _VFPEPTES(ph)GDEGEELGLPLLSTR_
WRAP53 Phosphorylation S54 -0.663 -0.543 _GDPPRLS(ph)PDPVAGSAVSQELR_
WRAP53 Phosphorylation S90 -0.716 -0.742 _EGDPVSLSTPLETEFGSPSELS(ph)PR_
WRAP53 Phosphorylation S85 -0.851 -0.870 _EGDPVSLSTPLETEFGS(ph)PSELS(ph)PR_

Background Information for WRAP53:





Protein-protein Interactions for WRAP53

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CHMP6 Cat. description Hein, Mann, Cell 2015
Category members IP bait CNTROB Cat. description Hein, Mann, Cell 2015
Category members IP bait GAR1 Cat. description Hein, Mann, Cell 2015
Category members IP bait PCDH1 Cat. description Hein, Mann, Cell 2015
Category members IP bait POLG2 Cat. description Hein, Mann, Cell 2015
Category members IP bait PTPN1 Cat. description Hein, Mann, Cell 2015
Category members IP bait RAP1B Cat. description Hein, Mann, Cell 2015
Category members IP bait RXRB Cat. description Hein, Mann, Cell 2015
Category members IP bait WRAP53 Cat. description Hein, Mann, Cell 2015
Category members IP bait ARHGAP25 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CRYL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM43A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM46A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GAR1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KIAA1683 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LYPD4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in WRAP53

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members WD40_repeat_dom IPR017986 1.39
Category members WD40_repeat IPR001680 0.52


Protein complexes (CORUM database) featuring WRAP53

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring WRAP53

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0003723 RNA binding Database INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005730 nucleolus Database 13.38
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Pathway Pathway_320 REACTOME_CELL_CYCLE 0 11.08
Category members Pathway Pathway_319 REACTOME_CHROMOSOME_MAINTENANCE 0 7.37
Category members Pathway Pathway_328 REACTOME_TELOMERE_MAINTENANCE 0 3.74
Category members Pathway Pathway_324 REACTOME_EXTENSION_OF_TELOMERES 0 0.33
Category members GO Category GO:0015030 Cajal body Database 0.04
Category members Disease phenotype Dyskeratosis_congenita Dyskeratosis congenita Database 0
Category members GO Category GO:0005697 telomerase holoenzyme complex Database 0
Category members GO Category GO:0032203 telomere formation via telomerase Database 0
Category members GO Category GO:0051973 positive regulation of telomerase activity Database 0


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