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Query: WDR74

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
WDR74 1 0.320 -0.950 1.210 -0.916 0.064

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
WDR74 Ubiquitylation K359 -1.818 _K(gl)LSGLEQPQGALQTR_
WDR74 Ubiquitylation K266 1.780 _LLGCLK(gl)GLAGSVR_

Background Information for WDR74:


Pubmed-WDR74 »
Uniprot-WDR74 »
Biogrid-WDR74 »
ProteomicsDB-WDR74 »

Tumorportal-WDR74 »
COSMIC-WDR74 »
GenomeRNAi-WDR74 »
Genecards-WDR74


Protein-protein Interactions for WDR74
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait BRWD3 Cat. description Hein, Mann, Cell 2015
Category members IP bait C17orf85 Cat. description Hein, Mann, Cell 2015
Category members IP bait GSPT1;GSPT2 Cat. description Hein, Mann, Cell 2015
Category members IP bait IBTK Cat. description Hein, Mann, Cell 2015
Category members IP bait JUNB Cat. description Hein, Mann, Cell 2015
Category members IP bait NOP56 Cat. description Hein, Mann, Cell 2015
Category members IP bait PDGFRA Cat. description Hein, Mann, Cell 2015
Category members IP bait PKN2 Cat. description Hein, Mann, Cell 2015
Category members IP bait RRBP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SRP72 Cat. description Hein, Mann, Cell 2015
Category members IP bait THOC5 Cat. description Hein, Mann, Cell 2015
Category members IP bait CARD8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CCNJL Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MAK16 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RPF1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in WDR74
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members WD40_repeat_dom IPR017986 1.39
Category members WD40_repeat IPR001680 0.52


Protein complexes (CORUM database) featuring WDR74
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring WDR74
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0016070 RNA metabolic process Database INF
Category members GO Category GO:0005730 nucleolus Database 13.38
Category members GO Category GO:0001825 blastocyst formation Database 0.09
Category members GO Category GO:0003674 molecular_function Database 0.08
Category members GO Category GO:0008150 biological_process Database 0


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