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Query: WBP11

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
WBP11 1 0.628 -2.030 3.570 -1.447 -0.619 -0.206 -1.722 -0.800

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
WBP11 Phosphorylation S237 0.291 0.449 _DEDMLYS(ph)PELAQR_
WBP11 Ubiquitylation K51 0.437 _MKDPK(gl)QIIR_
WBP11 Ubiquitylation K117 1.112 _KLEVEYEQK(gl)R_

Background Information for WBP11:





Protein-protein Interactions for WBP11

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait GBAS Cat. description Hein, Mann, Cell 2015
Category members IP bait KIF26B Cat. description Hein, Mann, Cell 2015
Category members IP bait PQBP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SPTLC2 Cat. description Hein, Mann, Cell 2015
Category members IP bait STK17B Cat. description Hein, Mann, Cell 2015
Category members IP bait WBP11 Cat. description Hein, Mann, Cell 2015
Category members IP bait HSD3B2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ID2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait JPH4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PPP1CA Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PPP1CC Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in WBP11

Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring WBP11

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 351 Spliceosome Database 9.3


Categories featuring WBP11

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0008380 RNA splicing Database 10.77
Category members Pathway Pathway_851 KEGG_SPLICEOSOME 0 7.94
Category members GO Category GO:0016607 nuclear speck Database 4.84
Category members GO Category GO:0003697 single-stranded DNA binding Database 4.24
Category members GO Category GO:0006397 mRNA processing Database 3.76
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0006364 rRNA processing Database 2.47
Category members GO Category GO:0050699 WW domain binding Database 0.36
Category members GO Category GO:0006396 RNA processing Database 0.17
Category members GO Category GO:0008599 protein phosphatase type 1 regulator activity Database 0.16


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