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Query: UNC45A

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
UNC45A 0 0.664 -0.500 0.440 0.473 0.144
UNC45A 0 0.664 -0.500 0.440 0.335

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
UNC45A Phosphorylation T15 -0.400 -0.160 _PAT(ph)PGASSVEQLRK_
UNC45A Ubiquitylation K516 -0.223 -0.882 _LGSAGGTDFSMK(gl)QFAEGSTLK_
UNC45A Ubiquitylation K93 0.714 _DGGDVK(gl)ALYR_
UNC45A Ubiquitylation K142 0.218 _NIGGQIQEK(gl)VR_
UNC45A Ubiquitylation K707 0.010 _ALIPLALEGTDVGQTK(gl)AAQALAK_

Background Information for UNC45A:


Pubmed-UNC45A »
Uniprot-UNC45A »
Biogrid-UNC45A »
ProteomicsDB-UNC45A »

Tumorportal-UNC45A »
COSMIC-UNC45A »
GenomeRNAi-UNC45A »
Genecards-UNC45A


Protein-protein Interactions for UNC45A
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ACTB Cat. description Hein, Mann, Cell 2015
Category members IP bait CAPZA2 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYH9 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO19 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO1C Cat. description Hein, Mann, Cell 2015
Category members IP bait XRCC3 Cat. description Hein, Mann, Cell 2015
Category members IP bait UNC45A Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in UNC45A
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members ARM-type_fold IPR016024 9.26
Category members TPR-contain_dom IPR013026 0.97
Category members TPR_repeat IPR019734 0.93
Category members UNC-45/Ring3 IPR024660 0


Protein complexes (CORUM database) featuring UNC45A
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring UNC45A
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005488 binding Database 9.32
Category members GO Category GO:0048471 perinuclear region of cytoplasm Database 0.39
Category members GO Category GO:0030154 cell differentiation Database 0.06
Category members GO Category GO:0007517 muscle organ development Database 0
Category members GO Category GO:0051879 Hsp90 protein binding Database 0
Category members GO Category GO:0061077 chaperone-mediated protein folding Database 0


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