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Query: UFD1L

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
UFD1L 1 3.433 -1.920 3.230 -0.672 -1.423

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
UFD1L Ubiquitylation K300 -0.072 0.804 _GIPNYEFK(gl)LGK_
UFD1L Phosphorylation S335 0.387 0.801 _FVAFSGEGQS(ph)LRK_
UFD1L Phosphorylation S330 0.281 0.670 _FVAFS(ph)GEGQSLRK_
UFD1L Ubiquitylation K211 -0.114 -0.012 _VMETK(gl)PDK_
UFD1L Ubiquitylation K45 -0.589 -0.227 _GGK(gl)IIMPPSALDQLSR_
UFD1L Phosphorylation S283 -1.549 -1.110 _KGVEPSPS(ph)PIKPGDIK_
UFD1L Ubiquitylation K315 -0.492 -1.302 _NSRPLVK(gl)K_
UFD1L Phosphorylation S281 -1.420 _KGVEPS(ph)PSPIKPGDIK_
UFD1L Ubiquitylation K291 -1.450 -2.430 _GVEPSPSPIKPGDIK(gl)R_
UFD1L Ubiquitylation K68 0.306 _LNITYPMLFK(gl)_
UFD1L Ubiquitylation K303 -0.352 _LGK(gl)ITFIR_

Background Information for UFD1L:


Pubmed-UFD1L »
Uniprot-UFD1L »
Biogrid-UFD1L »
ProteomicsDB-UFD1L »

Tumorportal-UFD1L »
COSMIC-UFD1L »
GenomeRNAi-UFD1L »
Genecards-UFD1L


Protein-protein Interactions for UFD1L
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ATG9A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM189B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLC17A2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SV2C Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in UFD1L
Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring UFD1L
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 5685 Membrane protein complex (VCP, UFD1L, SEC61B) Database 0


Categories featuring UFD1L
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0006511 ubiquitin-dependent protein catabolic process Database 3.57
Category members GO Category GO:0004843 ubiquitin-specific protease activity Database 3.28
Category members GO Category GO:0032403 protein complex binding Database 0.49
Category members Disease phenotype 22q11.2_Deletion_Syndrome 22q11.2 Deletion Syndrome Database 0.31
Category members GO Category GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process Database 0.23
Category members GO Category GO:0001501 skeletal system development Database 0
Category members GO Category GO:0005102 receptor binding Database 0


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