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Query: UBR4

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
UBR4 0 2.424 -0.920 1.020 -0.784 -0.202 -0.005

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
UBR4 Ubiquitylation K634 1.147 _QAPGEK(gl)GNILASR_
UBR4 Phosphorylation S178 0.789 0.678 _TLSDVEDQKELAS(ph)PVSPELR_
UBR4 Phosphorylation S2885 0.099 0.584 _TS(ph)PADHGGSVGSESGGSAVDSVAGEHSVSGR_
UBR4 Phosphorylation S2718 0.094 0.358 _HVTLPS(ph)SPR_
UBR4 Phosphorylation S2722 0.030 0.328 _S(ph)NTPMGDKDDDDDDDADEK_
UBR4 Ubiquitylation K4820 0.281 _GQVVTK(gl)TALLK_
UBR4 Ubiquitylation K366 -0.253 0.278 _TGSTSSK(gl)EDDYESDAATIVQK_
UBR4 Phosphorylation T2724 0.030 0.079 _SNT(ph)PMGDKDDDDDDDADEK_
UBR4 Phosphorylation S2719 0.011 0.010 _HVTLPSS(ph)PR_
UBR4 Phosphorylation S181 -0.014 -0.361 _TLSDVEDQKELASPVS(ph)PELR_
UBR4 Ubiquitylation K1150 -0.219 -0.464 _MAAETDPHK(gl)SSEITK_
UBR4 Phosphorylation S619 -3.459 -2.790 _AAPPPPPPPPPLES(ph)SPR_
UBR4 Phosphorylation S620 -3.459 -2.790 _AAPPPPPPPPPLES(ph)SPR_
UBR4 Ubiquitylation K3606 -1.378 _TVQAIVELK(gl)NKPAR_
UBR4 Ubiquitylation K3608 -1.378 _TVQAIVELK(gl)NKPAR_

Background Information for UBR4:


Pubmed-UBR4 »
Uniprot-UBR4 »
Biogrid-UBR4 »
ProteomicsDB-UBR4 »

Tumorportal-UBR4 »
COSMIC-UBR4 »
GenomeRNAi-UBR4 »
Genecards-UBR4


Protein-protein Interactions for UBR4
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait COPA Cat. description Hein, Mann, Cell 2015
Category members IP bait GORASP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MGP Cat. description Hein, Mann, Cell 2015
Category members IP bait NCK1 Cat. description Hein, Mann, Cell 2015
Category members IP bait RANBP2 Cat. description Hein, Mann, Cell 2015
Category members IP bait RAP1B Cat. description Hein, Mann, Cell 2015
Category members IP bait USF1;usf1 Cat. description Hein, Mann, Cell 2015
Category members IP bait USO1 Cat. description Hein, Mann, Cell 2015
Category members IP bait WIZ Cat. description Hein, Mann, Cell 2015
Category members IP bait XRCC3 Cat. description Hein, Mann, Cell 2015
Category members IP bait A1BG Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ACSM5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C18orf10 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C1orf87 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CCNG1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CHIA Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CPNE5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CRYL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CSHL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CST9 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EDA Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ERMAP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM73B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FIGF Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FSTL4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FUZ Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GML Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HYAL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait INSL5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KCMF1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait METTL2A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NRP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PI4KA Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PNPLA1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait POMC Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLX1A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait STX11 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TFDP3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VWA5A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WDR34 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in UBR4
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members ARM-type_fold IPR016024 9.26
Category members WD40_repeat_dom IPR017986 1.39
Category members Znf_N-recognin IPR003126 0
Category members Znf_N-recognin_met IPR013993 0


Protein complexes (CORUM database) featuring UBR4
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring UBR4
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005488 binding Database 9.32
Category members GO Category GO:0019048 modulation by virus of host morphology or physiology Database 7.81
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members Pathway Pathway_621 REACTOME_ADAPTIVE_IMMUNE_SYSTEM 0 4.72
Category members Pathway Pathway_458 REACTOME_IMMUNE_SYSTEM 0 3
Category members Pathway Pathway_764 REACTOME_CLASS_I_MHC_MEDIATED_ANTIGEN_PROCESSING_PRESENTATION 0 2.56
Category members Pathway Pathway_832 REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION 0 1.58
Category members GO Category GO:0005516 calmodulin binding Database 0.74
Category members GO Category GO:0005856 cytoskeleton Database 0.63
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members GO Category GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process Database 0.27
Category members GO Category GO:0004842 ubiquitin-protein ligase activity Database 0.24
Category members GO Category GO:0016874 ligase activity Database 0


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