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Query: UBQLN1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
UBQLN1 0 3.023 -0.470 1.020 0.070 0.121 -0.680 0.697
UBQLN1 0 3.023 -0.470 1.020 0.509 0.111 0.365

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
UBQLN1 Ubiquitylation K35 -0.248 0.186 _ASVK(gl)EFKEEISR_
UBQLN1 Phosphorylation S4 -0.049 _AES(ph)GES(ph)GGPPGSQDSAAGAEGAGAPAAAASAEPK_
UBQLN1 Phosphorylation S7 -0.049 _AES(ph)GES(ph)GGPPGSQDSAAGAEGAGAPAAAASAEPK_
UBQLN1 Ubiquitylation K38 0.479 _IMK(gl)VTVK_
UBQLN1 Ubiquitylation K45 -1.252 _TPK(gl)EKEEFAVPENSSVQQFK_
UBQLN1 Ubiquitylation K47 -0.328 _EK(gl)EEFAVPENSSVQQFK_

Background Information for UBQLN1:


Pubmed-UBQLN1 »
Uniprot-UBQLN1 »
Biogrid-UBQLN1 »
ProteomicsDB-UBQLN1 »

Tumorportal-UBQLN1 »
COSMIC-UBQLN1 »
GenomeRNAi-UBQLN1 »
Genecards-UBQLN1


Protein-protein Interactions for UBQLN1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait KDELR1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in UBQLN1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members ARM-type_fold IPR016024 9.26
Category members Rad60/SUMO_like IPR022617 1.93
Category members Ubiquitin-rel_dom IPR029071 1.79
Category members Ubiquitin-like IPR000626 1.61
Category members STI1_HS-bd IPR006636 0.44
Category members XPC-bd IPR015360 0.35
Category members UBA/Ts_N IPR000449 0.34
Category members UBA-like IPR009060 0.17
Category members UBA/transl_elong_EF1B_N_euk IPR015940 0.04


Protein complexes (CORUM database) featuring UBQLN1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 5209 Ubiquilin-proteasome complex Database 0.04


Categories featuring UBQLN1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005488 binding Database 9.32
Category members GO Category GO:0006289 nucleotide-excision repair Database 6.65
Category members GO Category GO:0003684 damaged DNA binding Database 4.54
Category members GO Category GO:0000502 proteasome complex Database 3.17
Category members GO Category GO:0043234 protein complex Database 2.73
Category members GO Category GO:0019904 protein domain specific binding Database 1.85
Category members Pathway Pathway_645 PID_CXCR4_PATHWAY 0 1.42
Category members GO Category GO:0005783 endoplasmic reticulum Database 0.62
Category members GO Category GO:0019900 kinase binding Database 0.45
Category members GO Category GO:0048471 perinuclear region of cytoplasm Database 0.39
Category members GO Category GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process Database 0.23
Category members GO Category GO:0034976 response to endoplasmic reticulum stress Database 0.06
Category members GO Category GO:0031396 regulation of protein ubiquitination Database 0
Category members GO Category GO:0071456 cellular response to hypoxia Database 0


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