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Query: UBA2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
UBA2 0 3.419 -1.510 1.640 -0.131 0.994 0.409

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
UBA2 Ubiquitylation K505 -0.878 1.332 _K(gl)LSEFGIR_
UBA2 Ubiquitylation K253 -0.323 0.349 _STGYDPVK(gl)LFTK_
UBA2 Ubiquitylation K409 -0.439 -0.042 _ILSGK(gl)IDQCR_
UBA2 Ubiquitylation K65 -0.036 -0.366 _QFLFQK(gl)K_
UBA2 Phosphorylation S207 -0.561 -0.428 _YLFNQLFGEEDADQEVS(ph)PDRADPEAAWEPTEAEAR_
UBA2 Ubiquitylation K324 0.043 -0.960 _LFSK(gl)SIETLR_
UBA2 Ubiquitylation K316 -1.087 -1.014 _DQQVLDVK(gl)SYAR_
UBA2 Ubiquitylation K77 -1.078 _AQVAK(gl)ESVLQFYPK_
UBA2 Ubiquitylation K241 -1.105 _ISTK(gl)EWAK_
UBA2 Ubiquitylation K623 0.163 -1.357 _LDEKENLSAK(gl)R_
UBA2 Ubiquitylation K420 -0.983 -1.831 _TIFLNK(gl)QPNPR_
UBA2 Ubiquitylation K164 -0.901 -1.888 _GVTECYECHPK(gl)PTQR_
UBA2 Ubiquitylation K557 -1.977 _VGPK(gl)QAEDAAK_
UBA2 Ubiquitylation K245 -0.801 -2.124 _EWAK(gl)STGYDPVK_

Background Information for UBA2:


Pubmed-UBA2 »
Uniprot-UBA2 »
Biogrid-UBA2 »
ProteomicsDB-UBA2 »

Tumorportal-UBA2 »
COSMIC-UBA2 »
GenomeRNAi-UBA2 »
Genecards-UBA2


Protein-protein Interactions for UBA2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait SAE1 Cat. description Hein, Mann, Cell 2015
Category members IP bait UBE2I Cat. description Hein, Mann, Cell 2015
Category members IP bait CPNE5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait UBE2I Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in UBA2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members ThiF_NAD_FAD-bd IPR000594 0.19
Category members Molybdenum_cofac_synth_MoeB IPR009036 0.19
Category members UBact_repeat IPR000127 0.08
Category members Ubiquitin-activating_enzyme IPR019572 0.08


Protein complexes (CORUM database) featuring UBA2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 5755 SUMO1-SUA1-UBA2 complex Database 0.49
Category members Corum 5756 SUA1-UBA2 complex Database 0.2


Categories featuring UBA2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members Pathway Pathway_621 REACTOME_ADAPTIVE_IMMUNE_SYSTEM 0 4.72
Category members Pathway Pathway_458 REACTOME_IMMUNE_SYSTEM 0 3
Category members Pathway Pathway_764 REACTOME_CLASS_I_MHC_MEDIATED_ANTIGEN_PROCESSING_PRESENTATION 0 2.56
Category members Pathway Pathway_888 KEGG_UBIQUITIN_MEDIATED_PROTEOLYSIS 0 2.22
Category members Pathway Pathway_832 REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION 0 1.58
Category members GO Category GO:0043085 positive regulation of catalytic activity Database 0.78
Category members GO Category GO:0008134 transcription factor binding Database 0.37
Category members GO Category GO:0016925 protein sumoylation Database 0.33
Category members GO Category GO:0046982 protein heterodimerization activity Database 0.28
Category members GO Category GO:0008641 small protein activating enzyme activity Database 0.26
Category members GO Category GO:0019948 SUMO activating enzyme activity Database 0.2
Category members GO Category GO:0008047 enzyme activator activity Database 0.15
Category members GO Category GO:0003824 catalytic activity Database 0.11
Category members GO Category GO:0006464 cellular protein modification process Database 0
Category members GO Category GO:0016874 ligase activity Database 0
Category members GO Category GO:0046872 metal ion binding Database 0


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