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Query: TUBB3

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
TUBB3 0 0.212 -0.769 -0.098 0.204 0.142 -0.012
TUBB3 0 0.212 -0.610

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
TUBB3 Ubiquitylation K58 -0.451 0.939 _ISVYYNEATGGK(gl)YVPR_

Background Information for TUBB3:


Pubmed-TUBB3 »
Uniprot-TUBB3 »
Biogrid-TUBB3 »
ProteomicsDB-TUBB3 »

Tumorportal-TUBB3 »
COSMIC-TUBB3 »
GenomeRNAi-TUBB3 »
Genecards-TUBB3


Protein-protein Interactions for TUBB3
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait BAG6;BAT3 Cat. description Hein, Mann, Cell 2015
Category members IP bait CDC16 Cat. description Hein, Mann, Cell 2015
Category members IP bait CDK1 Cat. description Hein, Mann, Cell 2015
Category members IP bait FAM190B Cat. description Hein, Mann, Cell 2015
Category members IP bait HNRNPD Cat. description Hein, Mann, Cell 2015
Category members IP bait MAD2L1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SYNCRIP Cat. description Hein, Mann, Cell 2015
Category members IP bait TUBA1C Cat. description Hein, Mann, Cell 2015
Category members IP bait WIZ Cat. description Hein, Mann, Cell 2015
Category members IP bait ADAMTS4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait APLNR Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait AVIL Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait BPNT1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C1orf85 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C9orf3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CBWD1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CCL22 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CD79A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CD79B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CDH13 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CHRM3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CHRM4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CLEC4E Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DDX39A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DEF8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DKKL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DNASE2B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DOCK5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EFNB3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EIF3F Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ENPP7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait F9 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM174A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM196A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAS Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FCGR3B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GDF9 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GML Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HS3ST2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IL12RB1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait INSL5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IQCF1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ISLR Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KIAA1967 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KLK11 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KLK5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KLK6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LAMP3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LGALS7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LRP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MAPK8IP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MUC20 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NPAS1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NRG1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait P2RX2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PCDH20 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PDDC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PLA2G10 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PLAUR Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PPARD Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PRG3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PRKCSH Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PROZ Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PRSS2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PRSS50 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RNF19B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RPL28 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RPS27 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SALL2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SCN2B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SIRT6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SKP2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLAMF1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLC5A5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLCO1B1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNX21 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SPACA1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ST8SIA4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait STK16 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SUSD4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TAF5L Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait THBS3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMCO3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMEM108 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMEM25 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TOMM22 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TPSB2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TRAC Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TSHB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TSPYL6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TUBA1A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TUBA4A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TUBB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TUBB2A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TUBB2B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TUBB3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VSIG1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WNT16 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WNT7A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait XAGE1A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait XCL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF695 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in TUBB3
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members GPCR_Rhodpsn IPR000276 2.56
Category members GPCR_Rhodpsn_7TM IPR017452 2.32
Category members Tubulin IPR000217 0
Category members Melcrt_ACTH_rcpt IPR001671 0
Category members Melancort_rcpt IPR001908 0
Category members Alpha_tubulin IPR002452 0
Category members Beta_tubulin IPR002453 0
Category members Gamma_tubulin IPR002454 0
Category members Delta_tubulin IPR002967 0
Category members Tubulin_FtsZ_GTPase IPR003008 0
Category members Epsilon_tubulin IPR004057 0
Category members Tub_FtsZ_C IPR008280 0
Category members Tubulin/FtsZ_2-layer-sand-dom IPR018316 0


Protein complexes (CORUM database) featuring TUBB3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring TUBB3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Pathway Pathway_11 REACTOME_METABOLISM_OF_PROTEINS 0 12.01
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0043234 protein complex Database 2.73
Category members GO Category GO:0007067 mitosis Database 2.23
Category members GO Category GO:0004930 G-protein coupled receptor activity Database 2.1
Category members GO Category GO:0007186 G-protein coupled receptor signaling pathway Database 1.53
Category members GO Category GO:0015630 microtubule cytoskeleton Database 1.34
Category members GO Category GO:0005874 microtubule Database 1.21
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members Pathway Pathway_742 REACTOME_PROTEIN_FOLDING 0 0.9
Category members Pathway Pathway_1026 KEGG_PATHOGENIC_ESCHERICHIA_COLI_INFECTION 0 0.45
Category members Pathway Pathway_1288 REACTOME_PREFOLDIN_MEDIATED_TRANSFER_OF_SUBSTRATE_TO_CCT_TRIC 0 0.4
Category members GO Category GO:0007017 microtubule-based process Database 0.3
Category members GO Category GO:0006184 GTP catabolic process Database 0.29
Category members GO Category GO:0030424 axon Database 0.23
Category members GO Category GO:0005525 GTP binding Database 0.16
Category members GO Category GO:0003924 GTPase activity Database 0.16
Category members GO Category GO:0007411 axon guidance Database 0.13
Category members Pathway Pathway_213 KEGG_GAP_JUNCTION 0 0.11
Category members Pathway Pathway_1296 REACTOME_FORMATION_OF_TUBULIN_FOLDING_INTERMEDIATES_BY_CCT_TRIC 0 0.08
Category members Pathway Pathway_1295 REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY 0 0.07
Category members Disease phenotype Congenital_fibrosis_of_extraocular_muscles Congenital fibrosis of extraocular muscles Database 0
Category members GO Category GO:0005200 structural constituent of cytoskeleton Database 0
Category members GO Category GO:0042277 peptide binding Database 0
Category members GO Category GO:0051258 protein polymerization Database 0


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