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Query: TUBB1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
TUBB1 0 0.353 -0.430 0.300 -0.769 -0.098 0.204 0.142 -0.012

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
TUBB1 Ubiquitylation K58 -0.451 0.939 _ISVYYNEATGGK(gl)YVPR_

Background Information for TUBB1:


Pubmed-TUBB1 »
Uniprot-TUBB1 »
Biogrid-TUBB1 »
ProteomicsDB-TUBB1 »

Tumorportal-TUBB1 »
COSMIC-TUBB1 »
GenomeRNAi-TUBB1 »
Genecards-TUBB1


Protein-protein Interactions for TUBB1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ACAD9 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ADAMTS4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ALPI Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ASTL Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C1orf85 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CBWD2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CELA1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CLEC5A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CRHBP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CTDSP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DOCK5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ENPP7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GABRG2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IL17RA Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KLHL33 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LIPG Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MFSD11 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MUC20 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NPAS1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait OLFM2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait OTC Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PLA2G10 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PRG2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PRKAB1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PRSS2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PRSS50 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PSG1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PSG8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RAPGEF5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RPGR Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SERPINC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SFRP4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SIRT6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TCTN1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TSPYL6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TUBB1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TUBB2B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TUBB3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WNT7A Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in TUBB1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Tubulin IPR000217 0
Category members Alpha_tubulin IPR002452 0
Category members Beta_tubulin IPR002453 0
Category members Gamma_tubulin IPR002454 0
Category members Delta_tubulin IPR002967 0
Category members Tubulin_FtsZ_GTPase IPR003008 0
Category members Epsilon_tubulin IPR004057 0
Category members Tub_FtsZ_C IPR008280 0
Category members Tubulin/FtsZ_2-layer-sand-dom IPR018316 0
Category members Misato_II_tubulin-like IPR019605 0


Protein complexes (CORUM database) featuring TUBB1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 3055 Nop56p-associated pre-rRNA complex Database INF
Category members Corum 1231 FIB-associated protein complex Database 0


Categories featuring TUBB1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Pathway Pathway_11 REACTOME_METABOLISM_OF_PROTEINS 0 12.01
Category members GO Category GO:0044267 cellular protein metabolic process Database 10.42
Category members GO Category GO:0006457 protein folding Database 4.93
Category members GO Category GO:0043234 protein complex Database 2.73
Category members GO Category GO:0015630 microtubule cytoskeleton Database 1.34
Category members GO Category GO:0005874 microtubule Database 1.21
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members Pathway Pathway_742 REACTOME_PROTEIN_FOLDING 0 0.9
Category members GO Category GO:0051084 'de novo' posttranslational protein folding Database 0.63
Category members Pathway Pathway_1026 KEGG_PATHOGENIC_ESCHERICHIA_COLI_INFECTION 0 0.45
Category members Pathway Pathway_1288 REACTOME_PREFOLDIN_MEDIATED_TRANSFER_OF_SUBSTRATE_TO_CCT_TRIC 0 0.4
Category members GO Category GO:0007017 microtubule-based process Database 0.3
Category members GO Category GO:0006184 GTP catabolic process Database 0.29
Category members GO Category GO:0051225 spindle assembly Database 0.25
Category members GO Category GO:0005525 GTP binding Database 0.16
Category members GO Category GO:0003924 GTPase activity Database 0.16
Category members Pathway Pathway_213 KEGG_GAP_JUNCTION 0 0.11
Category members Pathway Pathway_1296 REACTOME_FORMATION_OF_TUBULIN_FOLDING_INTERMEDIATES_BY_CCT_TRIC 0 0.08
Category members Pathway Pathway_1295 REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY 0 0.07
Category members Disease phenotype Autosomal_dominant_macrothrombocytopenia Autosomal dominant macrothrombocytopenia Database 0
Category members GO Category GO:0005200 structural constituent of cytoskeleton Database 0
Category members GO Category GO:0051258 protein polymerization Database 0


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