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Query: TSEN54

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
TSEN54 0 -0.282 -1.740 2.450

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
TSEN54 Ubiquitylation K489 -0.738 -1.994 _MCISGFDEPVPDLCSLK(gl)R_

Background Information for TSEN54:


Pubmed-TSEN54 »
Uniprot-TSEN54 »
Biogrid-TSEN54 »
ProteomicsDB-TSEN54 »

Tumorportal-TSEN54 »
COSMIC-TSEN54 »
GenomeRNAi-TSEN54 »
Genecards-TSEN54


Protein-protein Interactions for TSEN54
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait AMMECR1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TSEN15 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TSEN2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in TSEN54
Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring TSEN54
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 5283 tRNA splicing endonuclease Database 0.17
Category members Corum 5284 RNA endonuclease (SEN2deltaEx8, SEN54, CLP1) Database 0


Categories featuring TSEN54
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005730 nucleolus Database 13.38
Category members GO Category GO:0006397 mRNA processing Database 3.76
Category members GO Category GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation Database 0.22
Category members Disease phenotype Pontocerebellar_Hypoplasia_Type_2_and_Type_4 Pontocerebellar Hypoplasia Type 2 and Type 4 Database 0.18
Category members Disease phenotype Pontocerebellar_hypoplasia_type_1 Pontocerebellar hypoplasia type 1 Database 0
Category members Disease phenotype Pontocerebellar_hypoplasia_type_2 Pontocerebellar hypoplasia type 2 Database 0


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