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Query: TSC22D3

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
TSC22D3 1 2.877 0.960 -0.800
TSC22D3 1 2.877 0.960 -0.800 -0.814

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
TSC22D3 Ubiquitylation K122 4.513 _EEVEILK(gl)EQIR_
TSC22D3 Phosphorylation S102 -0.822 _TLAS(ph)PEQLEK_
TSC22D3 Ubiquitylation K131 -1.167 -1.192 _ELVEK(gl)NSQLER_
TSC22D3 Ubiquitylation K143 -1.436 _ENTLLK(gl)TLASPEQLEK_

Background Information for TSC22D3:


Pubmed-TSC22D3 »
Uniprot-TSC22D3 »
Biogrid-TSC22D3 »
ProteomicsDB-TSC22D3 »

Tumorportal-TSC22D3 »
COSMIC-TSC22D3 »
GenomeRNAi-TSC22D3 »
Genecards-TSC22D3


Protein-protein Interactions for TSC22D3
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CSK Cat. description Hein, Mann, Cell 2015
Category members IP bait FIGNL1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CDC42SE2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ENDOV Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM117B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KIAA1683 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RCCD1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SIRT6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TSC22D3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait UBE2CBP Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in TSC22D3
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members TSC-22_Dip_Bun IPR000580 0.08


Protein complexes (CORUM database) featuring TSC22D3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring TSC22D3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0003700 sequence-specific DNA binding transcription factor activity Database 0.63
Category members GO Category GO:0043066 negative regulation of apoptotic process Database 0.6
Category members GO Category GO:0055085 transmembrane transport Database 0.12
Category members GO Category GO:0070236 negative regulation of activation-induced cell death of T cells Database 0.07
Category members GO Category GO:0000122 negative regulation of transcription from RNA polymerase II promoter Database 0.02
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0006970 response to osmotic stress Database 0
Category members GO Category GO:0007589 body fluid secretion Database 0
Category members GO Category GO:0034220 ion transmembrane transport Database 0
Category members GO Category GO:0043426 MRF binding Database 0
Category members GO Category GO:0048642 negative regulation of skeletal muscle tissue development Database 0


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