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Query: TRIP11

This is a cancer-associated gene according to the Sanger cancer gene census.

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
TRIP11 0 -0.992 -0.180 0.110

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
TRIP11 Phosphorylation S1891 -0.048 0.160 _LSVHDMKPLDS(ph)PGR_
TRIP11 Ubiquitylation K419 -0.745 -0.469 _LSSLNQDNSLAEDNLK(gl)LK_

Background Information for TRIP11:





Protein-protein Interactions for TRIP11

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait DCTN1 Cat. description Hein, Mann, Cell 2015
Category members IP bait HAUS1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYH6 Cat. description Hein, Mann, Cell 2015
Category members IP bait SIDT2 Cat. description Hein, Mann, Cell 2015
Category members IP bait TRIP11 Cat. description Hein, Mann, Cell 2015
Category members IP bait TUBA3C;TUBA3E Cat. description Hein, Mann, Cell 2015
Category members IP bait ASB7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait BFSP2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EXOC3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in TRIP11

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members GRIP IPR000237 0.08
Category members Ribosomal_L29 IPR001854 0


Protein complexes (CORUM database) featuring TRIP11

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring TRIP11

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0003735 structural constituent of ribosome Database INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0006412 translation Database INF
Category members GO Category GO:0005840 ribosome Database 12.2
Category members Human mutations Sanger_cancer_genes Sanger cancer genes Database 4.88
Category members GO Category GO:0003713 transcription coactivator activity Database 3.68
Category members GO Category GO:0006366 transcription from RNA polymerase II promoter Database 0.96
Category members GO Category GO:0005856 cytoskeleton Database 0.63
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0043231 intracellular membrane-bounded organelle Database 0.43
Category members GO Category GO:0005622 intracellular Database 0.32
Category members GO Category GO:0005794 Golgi apparatus Database 0.27
Category members GO Category GO:0000042 protein targeting to Golgi Database 0.2
Category members GO Category GO:0003281 ventricular septum development Database 0


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