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Query: TNPO3

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
TNPO3 1 5.928 -1.850 2.990
TNPO3 1 5.928 -1.850 2.990 0.464 0.770 0.299

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
TNPO3 Ubiquitylation K68 0.538 0.867 _QDVESCYFAAQTMK(gl)MK_

Background Information for TNPO3:





Protein-protein Interactions for TNPO3

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait AK7 Cat. description Hein, Mann, Cell 2015
Category members IP bait IMMT Cat. description Hein, Mann, Cell 2015
Category members IP bait JAK3 Cat. description Hein, Mann, Cell 2015
Category members IP bait JUNB Cat. description Hein, Mann, Cell 2015
Category members IP bait PPP2R3A Cat. description Hein, Mann, Cell 2015
Category members IP bait RAD18 Cat. description Hein, Mann, Cell 2015
Category members IP bait SEPT6 Cat. description Hein, Mann, Cell 2015
Category members IP bait ATP2B2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait BCAM Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C19orf75 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C1orf63 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CD274 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CD70 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CLK3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait COMTD1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FCGRT Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FZD10 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HTR2C Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LUC7L Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LYPD3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MICA Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait OPRM1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait P2RX4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait P2RX5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait P2RY12 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PTGER3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RP2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SCARA3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SCN2B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ST6GAL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait STX5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMEM171 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMEM206 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TNFRSF1A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VASN Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VIPR2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VSIG1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VSIG2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in TNPO3

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members ARM-type_fold IPR016024 9.26
Category members Exportin-1/Importin-b-like IPR013598 0


Protein complexes (CORUM database) featuring TNPO3

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring TNPO3

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005488 binding Database 9.32
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0043231 intracellular membrane-bounded organelle Database 0.43
Category members Disease phenotype Primary_biliary_cirrhosis Primary biliary cirrhosis Database 0
Category members GO Category GO:0004872 receptor activity Database 0
Category members GO Category GO:0006810 transport Database 0


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