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Query: TMEM106B

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
TMEM106B 0 0.965 -0.240 -0.310

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
TMEM106B Ubiquitylation K164 0.965 _SIDVK(gl)YIGVK_
TMEM106B Ubiquitylation K179 0.875 _SAYVSYDVQK(gl)R_

Background Information for TMEM106B:





Protein-protein Interactions for TMEM106B

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait BTNL8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in TMEM106B

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members DUF1356_TMEM106 IPR009790 0


Protein complexes (CORUM database) featuring TMEM106B

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring TMEM106B

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0005765 lysosomal membrane Database 0.82
Category members GO Category GO:0003674 molecular_function Database 0.08
Category members Disease phenotype FRONTOTEMPORAL_DEMENTIA_AND/OR_AMYOTROPHIC_LATERAL_SCLEROSIS FRONTOTEMPORAL DEMENTIA AND/OR AMYOTROPHIC LATERAL SCLEROSIS Database 0
Category members Disease phenotype FRONTOTEMPORAL_LOBAR_DEGENERATION_WITH_TDP43_INCLUSIONS_GRN-RELATED FRONTOTEMPORAL LOBAR DEGENERATION WITH TDP43 INCLUSIONS GRN-RELATED Database 0
Category members GO Category GO:0005575 cellular_component Database 0
Category members GO Category GO:0008150 biological_process Database 0
Category members GO Category GO:0031902 late endosome membrane Database 0


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