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Query: TMED4

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
TMED4 1 7.703 -2.070 4.060 1.323 1.469

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
TMED4 Ubiquitylation K152 0.929 _DK(gl)LTELQLR_
TMED4 Ubiquitylation K172 -0.449 0.792 _QLLDQVEQIQK(gl)EQDYQR_
TMED4 Ubiquitylation K128 -1.012 0.777 _MALFAGGK(gl)LR_
TMED4 Ubiquitylation K224 -0.725 0.426 _SFFEAK(gl)K_
TMED4 Ubiquitylation K63 0.311 _TQMWDK(gl)QK_
TMED4 Ubiquitylation K65 -0.078 _TQMWDKQK(gl)_

Background Information for TMED4:


Pubmed-TMED4 »
Uniprot-TMED4 »
Biogrid-TMED4 »
ProteomicsDB-TMED4 »

Tumorportal-TMED4 »
COSMIC-TMED4 »
GenomeRNAi-TMED4 »
Genecards-TMED4


Protein-protein Interactions for TMED4
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait DENND6A Cat. description Hein, Mann, Cell 2015
Category members IP bait TMED10 Cat. description Hein, Mann, Cell 2015
Category members IP bait TMED2 Cat. description Hein, Mann, Cell 2015
Category members IP bait CDK5RAP3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CHST8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FGF3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GORASP2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HTR3C Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IL13RA2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LIPG Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SCN3B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SPPL2B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMED10 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMED2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMED3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in TMED4
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members GOLD IPR009038 0.12


Protein complexes (CORUM database) featuring TMED4
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring TMED4
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0015031 protein transport Database 3.48
Category members GO Category GO:0005789 endoplasmic reticulum membrane Database 1.57
Category members GO Category GO:0004871 signal transducer activity Database 0
Category members GO Category GO:0006810 transport Database 0
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling Database 0


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