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Query: TARS

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
TARS 0 2.263 -0.100 0.500 0.266 0.302
TARS 0 2.263 -0.100 0.500 -0.028

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
TARS Ubiquitylation K264 0.964 _ETLLAMFK(gl)YNK_
TARS Ubiquitylation K321 0.812 _NSSTYWEGK(gl)ADMETLQR_
TARS Ubiquitylation K750 0.519 _SK(gl)QAEEEF_
TARS Ubiquitylation K352 0.476 _FQEEAK(gl)NR_
TARS Ubiquitylation K745 0.454 _LQQLK(gl)EFR_
TARS Ubiquitylation K276 0.228 0.361 _ILNEK(gl)VNTPTTTVYR_
TARS Ubiquitylation K342 0.258 0.331 _MLK(gl)EWEK_
TARS Ubiquitylation K694 0.265 _FMADIDLDPGCTLNKK(gl)_
TARS Ubiquitylation K693 0.261 _FM(ox)ADIDLDPGCTLNK(gl)K_
TARS Ubiquitylation K669 -0.594 0.065 _QVMVVPVGPTCDEYAQK(gl)VR_
TARS Ubiquitylation K91 0.059 _VTLPDGK(gl)QVDAESWK_
TARS Ubiquitylation K246 0.057 _IIKEK(gl)QAFER_
TARS Ubiquitylation K75 -0.413 _AEHDSILAEK(gl)AEK_

Background Information for TARS:


Pubmed-TARS »
Uniprot-TARS »
Biogrid-TARS »
ProteomicsDB-TARS »

Tumorportal-TARS »
COSMIC-TARS »
GenomeRNAi-TARS »
Genecards-TARS


Protein-protein Interactions for TARS
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait BRWD3 Cat. description Hein, Mann, Cell 2015
Category members IP bait MAX Cat. description Hein, Mann, Cell 2015
Category members IP bait CCDC102B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EIF4E2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in TARS
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members aa-tRNA-synth_II IPR006195 0.24
Category members tRNA_SAD IPR012947 0.23
Category members Thr/Ala-tRNA-synth_IIc_edit IPR018163 0.08
Category members aa-tRNA-synt_IIb_cons-dom IPR002314 0
Category members Thr-tRNA-ligase_IIa IPR002320 0
Category members TGS IPR004095 0
Category members Anticodon-bd IPR004154 0
Category members TGS-like IPR012676 0


Protein complexes (CORUM database) featuring TARS
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring TARS
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0006412 translation Database INF
Category members GO Category GO:0010467 gene expression Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0000166 nucleotide binding Database 5.91
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members Pathway Pathway_201 REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION 0 3.57
Category members GO Category GO:0015629 actin cytoskeleton Database 2.22
Category members Pathway Pathway_202 REACTOME_TRNA_AMINOACYLATION 0 1.34
Category members GO Category GO:0006418 tRNA aminoacylation for protein translation Database 0.91
Category members Pathway Pathway_409 KEGG_AMINOACYL_TRNA_BIOSYNTHESIS 0 0.82
Category members GO Category GO:0016876 ligase activity, forming aminoacyl-tRNA and related compounds Database 0.42
Category members GO Category GO:0004812 aminoacyl-tRNA ligase activity Database 0.41
Category members GO Category GO:0004829 threonine-tRNA ligase activity Database 0
Category members GO Category GO:0006435 threonyl-tRNA aminoacylation Database 0
Category members GO Category GO:0042803 protein homodimerization activity Database 0
Category members GO Category GO:0043039 tRNA aminoacylation Database 0


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