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Query: TAF15

This is a cancer-associated gene according to the Sanger cancer gene census.

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
TAF15 0 0.502 -0.193 -0.755 0.254 0.188 0.314

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence

Background Information for TAF15:





Protein-protein Interactions for TAF15

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait FUS Cat. description Hein, Mann, Cell 2015
Category members IP bait HNRNPA1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MATR3 Cat. description Hein, Mann, Cell 2015
Category members IP bait MED12 Cat. description Hein, Mann, Cell 2015
Category members IP bait PPP1CB Cat. description Hein, Mann, Cell 2015
Category members IP bait SNRNP70 Cat. description Hein, Mann, Cell 2015
Category members IP bait SRSF1 Cat. description Hein, Mann, Cell 2015
Category members IP bait TAF15 Cat. description Hein, Mann, Cell 2015


Protein Domains in TAF15

Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring TAF15

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 1332 Large Drosha complex Database 0.08
Category members Corum 509 TFIID complex Database 0


Categories featuring TAF15

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members DDR Literature pubmedid:24332808 Marechal et al., 2014 RPA-mediated recruitment INF
Category members GO Category GO:0003723 RNA binding Database INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members DDR Literature pubmedid:24055347 Jungmichel et al., 2013 UV-stimulated poly(ADP-Ribosyl)ation targets Jungmichel et al., 2013 INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0000166 nucleotide binding Database 5.91
Category members Human mutations Sanger_cancer_genes Sanger cancer genes Database 4.88
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0003676 nucleic acid binding Database 0.83
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members GO Category GO:0045893 positive regulation of transcription, DNA-dependent Database 0.28


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