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Query: SRSF12

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SRSF12 2 4.815 1.580 -1.250 0.206 0.220
SRSF12 2 4.815 1.580 -1.250 0.111 -0.769 0.355 0.430 0.359

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SRSF12 Phosphorylation S148 1.666 1.828 _RFSYS(ph)QSK_
SRSF12 Phosphorylation S146 2.087 1.611 _RFS(ph)YSQSK_
SRSF12 Phosphorylation S133 0.913 1.008 _S(ph)FDYNYR_
SRSF12 Phosphorylation S131 1.611 0.977 _S(ph)RSFDYNYR_
SRSF12 Phosphorylation S223 0.311 _HSDSIARS(ph)PCK_

Background Information for SRSF12:


Pubmed-SRSF12 »
Uniprot-SRSF12 »
Biogrid-SRSF12 »
ProteomicsDB-SRSF12 »

Tumorportal-SRSF12 »
COSMIC-SRSF12 »
GenomeRNAi-SRSF12 »
Genecards-SRSF12


Protein-protein Interactions for SRSF12
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait C16orf88 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CLK2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CLK3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GSPT2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HIST1H1T Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LUC7L2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NOL12 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RPL7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNIP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNRNP70 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TRA2A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait U2AF2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZC3H18 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in SRSF12
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members RRM_dom IPR000504 4.34


Protein complexes (CORUM database) featuring SRSF12
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring SRSF12
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0003723 RNA binding Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0000166 nucleotide binding Database 5.91
Category members GO Category GO:0051082 unfolded protein binding Database 3.74
Category members GO Category GO:0048025 negative regulation of mRNA splicing, via spliceosome Database 2.79
Category members GO Category GO:0003676 nucleic acid binding Database 0.83
Category members GO Category GO:0050733 RS domain binding Database 0.58
Category members GO Category GO:0000381 regulation of alternative mRNA splicing, via spliceosome Database 0.5
Category members GO Category GO:0000395 mRNA 5'-splice site recognition Database 0.43
Category members GO Category GO:0016482 cytoplasmic transport Database 0.29
Category members GO Category GO:0000244 spliceosomal tri-snRNP complex assembly Database 0.15


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