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Query: SRP14

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SRP14 2 3.104 1.530 -0.610 0.030 -0.204 0.083 0.069 -0.488

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SRP14 Ubiquitylation K55 1.725 1.889 _KGTVEGFEPADNK(gl)CLLR_
SRP14 Ubiquitylation K32 1.539 _TSGSVYITLKK(gl)_
SRP14 Ubiquitylation K74 0.600 1.019 _ISTVVSSK(gl)EVNK_
SRP14 Ubiquitylation K78 0.627 0.893 _EVNK(gl)FQMAYSNLLR_
SRP14 Ubiquitylation K43 0.255 0.812 _K(gl)GTVEGFEPADNK_
SRP14 Ubiquitylation K96 0.206 _ANMDGLKK(gl)_
SRP14 Ubiquitylation K95 0.347 _ANMDGLK(gl)K_

Background Information for SRP14:


Pubmed-SRP14 »
Uniprot-SRP14 »
Biogrid-SRP14 »
ProteomicsDB-SRP14 »

Tumorportal-SRP14 »
COSMIC-SRP14 »
GenomeRNAi-SRP14 »
Genecards-SRP14


Protein-protein Interactions for SRP14
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CLCN2 Cat. description Hein, Mann, Cell 2015
Category members IP bait EIF3A Cat. description Hein, Mann, Cell 2015
Category members IP bait KLC2 Cat. description Hein, Mann, Cell 2015
Category members IP bait RPL10 Cat. description Hein, Mann, Cell 2015
Category members IP bait RRBP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SRP68 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SRP9 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in SRP14
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Antifreeze_1 IPR000104 0.24
Category members Signal_recog_particle_SRP9/14 IPR009018 0.17


Protein complexes (CORUM database) featuring SRP14
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 3055 Nop56p-associated pre-rRNA complex Database INF


Categories featuring SRP14
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Pathway Pathway_456 REACTOME_TRANSLATION 0 INF
Category members Pathway Pathway_459 REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE 0 INF
Category members GO Category GO:0003723 RNA binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0006412 translation Database INF
Category members GO Category GO:0006614 SRP-dependent cotranslational protein targeting to membrane Database INF
Category members GO Category GO:0010467 gene expression Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Pathway Pathway_11 REACTOME_METABOLISM_OF_PROTEINS 0 12.01
Category members GO Category GO:0044267 cellular protein metabolic process Database 10.42
Category members Pathway Pathway_914 KEGG_PROTEIN_EXPORT 0 0.7
Category members GO Category GO:0042493 response to drug Database 0.66
Category members GO Category GO:0045047 protein targeting to ER Database 0.62
Category members GO Category GO:0048500 signal recognition particle Database 0.62
Category members GO Category GO:0005786 signal recognition particle, endoplasmic reticulum targeting Database 0.46
Category members GO Category GO:0006613 cotranslational protein targeting to membrane Database 0.31
Category members GO Category GO:0008312 7S RNA binding Database 0.31
Category members GO Category GO:0030942 endoplasmic reticulum signal peptide binding Database 0.08


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