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Query: SRD5A3

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SRD5A3 0 1.106 -0.030 -0.060

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SRD5A3 Ubiquitylation K193 1.106 _NAYITGK(gl)NLLMQAR_
SRD5A3 Ubiquitylation K302 0.408 _SK(gl)FVSYPK_
SRD5A3 Ubiquitylation K56 -0.776 _TK(gl)CGEPSRPAACR_

Background Information for SRD5A3:


Pubmed-SRD5A3 »
Uniprot-SRD5A3 »
Biogrid-SRD5A3 »
ProteomicsDB-SRD5A3 »

Tumorportal-SRD5A3 »
COSMIC-SRD5A3 »
GenomeRNAi-SRD5A3 »
Genecards-SRD5A3


Protein-protein Interactions for SRD5A3
Show screen data for Category Name and Description Link to cat description Data Source


Protein Domains in SRD5A3
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members 3-oxo-5_a-steroid_4-DH_C IPR001104 0


Protein complexes (CORUM database) featuring SRD5A3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring SRD5A3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0005789 endoplasmic reticulum membrane Database 1.57
Category members GO Category GO:0005783 endoplasmic reticulum Database 0.62
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members GO Category GO:0006488 dolichol-linked oligosaccharide biosynthetic process Database 0.28
Category members GO Category GO:0006486 protein glycosylation Database 0.21
Category members GO Category GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor Database 0.03
Category members Pathway Pathway_174 REACTOME_ANDROGEN_BIOSYNTHESIS 0 0
Category members Pathway Pathway_4 REACTOME_METABOLISM_OF_LIPIDS_AND_LIPOPROTEINS 0 0
Category members Pathway Pathway_69 REACTOME_STEROID_HORMONES 0 0
Category members Pathway Pathway_70 REACTOME_METABOLISM_OF_STEROID_HORMONES_AND_VITAMINS_A_AND_D 0 0
Category members Pathway Pathway_89 KEGG_STEROID_HORMONE_BIOSYNTHESIS 0 0
Category members Disease phenotype Congenital_Disorders_of_Glycosylation Congenital Disorders of Glycosylation Database 0
Category members GO Category GO:0003865 3-oxo-5-alpha-steroid 4-dehydrogenase activity Database 0
Category members GO Category GO:0006629 lipid metabolic process Database 0
Category members GO Category GO:0006702 androgen biosynthetic process Database 0
Category members GO Category GO:0008202 steroid metabolic process Database 0
Category members GO Category GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors Database 0
Category members GO Category GO:0019348 dolichol metabolic process Database 0
Category members GO Category GO:0047751 cholestenone 5-alpha-reductase activity Database 0


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