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Query: SRCAP

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SRCAP 0 2.902 -1.460 2.340 0.206 0.736 0.502 0.216 0.151

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SRCAP Phosphorylation S3148 -0.201 -0.542 _RAGAPVGGS(ph)PGLAK_
SRCAP Phosphorylation S3016 -0.834 -0.727 _NPPS(ph)PRPSQLPVLDR_
SRCAP Phosphorylation S3020 -1.240 -0.849 _NPPSPRPS(ph)QLPVLDR_
SRCAP Phosphorylation S568 -0.959 -0.850 _DEEQSEADAGS(ph)GPPTPGPTTLGPK_
SRCAP Phosphorylation S1859 -1.239 -1.210 _SGPPS(ph)PPSTATSFGGPRPR_
SRCAP Phosphorylation T572 -0.798 -1.262 _DEEQSEADAGSGPPT(ph)PGPTTLGPK_
SRCAP Phosphorylation S2790 0.029 -1.530 _GAASTLVPGVSETSASPGS(ph)PSVR_

Background Information for SRCAP:


Pubmed-SRCAP »
Uniprot-SRCAP »
Biogrid-SRCAP »
ProteomicsDB-SRCAP »

Tumorportal-SRCAP »
COSMIC-SRCAP »
GenomeRNAi-SRCAP »
Genecards-SRCAP


Protein-protein Interactions for SRCAP
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CREBBP Cat. description Hein, Mann, Cell 2015
Category members IP bait DIS3L Cat. description Hein, Mann, Cell 2015
Category members IP bait MAU2 Cat. description Hein, Mann, Cell 2015
Category members IP bait NUF2 Cat. description Hein, Mann, Cell 2015
Category members IP bait PDK1 Cat. description Hein, Mann, Cell 2015
Category members IP bait PPP2R1A Cat. description Hein, Mann, Cell 2015
Category members IP bait RASSF1 Cat. description Hein, Mann, Cell 2015
Category members IP bait RNF168 Cat. description Hein, Mann, Cell 2015
Category members IP bait RUVBL1 Cat. description Hein, Mann, Cell 2015
Category members IP bait RUVBL2 Cat. description Hein, Mann, Cell 2015
Category members IP bait SOGA1 Cat. description Hein, Mann, Cell 2015
Category members IP bait TIPIN Cat. description Hein, Mann, Cell 2015
Category members IP bait TUBA3C;TUBA3E Cat. description Hein, Mann, Cell 2015
Category members IP bait WASH3P Cat. description Hein, Mann, Cell 2015
Category members IP bait YEATS4 Cat. description Hein, Mann, Cell 2015
Category members IP bait ACTBL2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ACTR6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CARD8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HIST1H2BA Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NFATC2IP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait P4HA3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait QPRT Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RUVBL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RUVBL2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait YEATS4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in SRCAP
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members SNF2_N IPR000330 3.38
Category members P-loop_NTPase IPR027417 2.83
Category members Helicase_C IPR001650 2.48
Category members Helicase_ATP-bd IPR014001 2.48
Category members HAS_subgr IPR013999 0.68
Category members Helicase/SANT-assoc_DNA-bd IPR014012 0.68
Category members CD225/Dispanin_fam IPR007593 0
Category members AT_hook_DNA-bd_motif IPR017956 0
Category members AT_hook-like IPR020478 0


Protein complexes (CORUM database) featuring SRCAP
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 1413 NCOR1 complex Database 0.65
Category members Corum 799 DMAP1-associated complex Database 0.05
Category members Corum 304 SRCAP-associated chromatin remodeling complex Database 0


Categories featuring SRCAP
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0019048 modulation by virus of host morphology or physiology Database 7.81
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0003713 transcription coactivator activity Database 3.68
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0043234 protein complex Database 2.73
Category members GO Category GO:0004386 helicase activity Database 2.49
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0016573 histone acetylation Database 1.24
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0003676 nucleic acid binding Database 0.83
Category members GO Category GO:0004402 histone acetyltransferase activity Database 0.56
Category members GO Category GO:0005794 Golgi apparatus Database 0.27
Category members GO Category GO:0006357 regulation of transcription from RNA polymerase II promoter Database 0.19


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