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Query: SPRTN

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SPRTN 0 -0.352 -0.430 0.360

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SPRTN Ubiquitylation K424 -1.053 0.412 _TVFDNFFIKK(gl)_
SPRTN Ubiquitylation K341 -0.868 0.142 _VSFANQK(gl)AFR_
SPRTN Ubiquitylation K423 -1.105 0.106 _LEDKTVFDNFFIK(gl)K_
SPRTN Ubiquitylation K376 -0.843 0.037 _VSSSK(gl)ISLR_
SPRTN Ubiquitylation K361 -0.560 _ISVTVGNIPK(gl)NSVSSSSQR_
SPRTN Ubiquitylation K221 -1.326 _IKEPENYSKK(gl)_
SPRTN Ubiquitylation K407 -2.258 -1.395 _VTESASVM(ox)PSQDVSGSEDTFPNK(gl)RPR_
SPRTN Ubiquitylation K220 -1.167 -1.533 _IKEPENYSK(gl)K_
SPRTN Ubiquitylation K98 -1.603 _LSEPLLK(gl)LRPR_
SPRTN Ubiquitylation K384 -1.719 -1.999 _NSSK(gl)VTESASVMPSQDVSGSEDTFPNKRPR_
SPRTN Ubiquitylation K227 -1.331 -3.032 _AK(gl)LGKEPVLAAENK_
SPRTN Ubiquitylation K213 -1.872 _IK(gl)EPENYSK_
SPRTN Phosphorylation S268 -0.353 _GYVLGETSNLPS(ph)PGK_
SPRTN Ubiquitylation K414 -0.771 _LEDK(gl)TVFDNFFIK_

Background Information for SPRTN:





Protein-protein Interactions for SPRTN

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait EMC2 Cat. description Hein, Mann, Cell 2015
Category members IP bait SPRTN Cat. description Hein, Mann, Cell 2015


Protein Domains in SPRTN

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members SprT-like_domain IPR006640 0
Category members Znf_Rad18_put IPR006642 0


Protein complexes (CORUM database) featuring SPRTN

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring SPRTN

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0006281 DNA repair Database INF
Category members GO Category GO:0016607 nuclear speck Database 4.84
Category members GO Category GO:0005694 chromosome Database 3.87
Category members GO Category GO:0006974 cellular response to DNA damage stimulus Database 3.57
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0043130 ubiquitin binding Database 1.22
Category members GO Category GO:0009411 response to UV Database 0.79
Category members GO Category GO:0070530 K63-linked polyubiquitin binding Database 0.35
Category members GO Category GO:0019985 translesion synthesis Database 0.05
Category members GO Category GO:0031398 positive regulation of protein ubiquitination Database 0
Category members GO Category GO:0046872 metal ion binding Database 0


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