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Query: SPINT2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SPINT2 0 0.789 -0.730 0.530

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SPINT2 Ubiquitylation K247 -0.197 0.456 _TVWSSGDDK(gl)EQLVK(gl)NTYVL_
SPINT2 Ubiquitylation K87 0.191 _K(gl)CATVTENATGDLATSR_
SPINT2 Ubiquitylation K242 -0.369 0.037 _TVWSSGDDK(gl)EQLVK(gl)NTYVL_

Background Information for SPINT2:


Pubmed-SPINT2 »
Uniprot-SPINT2 »
Biogrid-SPINT2 »
ProteomicsDB-SPINT2 »

Tumorportal-SPINT2 »
COSMIC-SPINT2 »
GenomeRNAi-SPINT2 »
Genecards-SPINT2


Protein-protein Interactions for SPINT2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait FAM189B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SPINT2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in SPINT2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Prot_inh_Kunz-m IPR002223 0.05


Protein complexes (CORUM database) featuring SPINT2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring SPINT2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005576 extracellular region Database 10.9
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0004867 serine-type endopeptidase inhibitor activity Database 1.42
Category members GO Category GO:0006928 cellular component movement Database 0.24
Category members GO Category GO:0010951 negative regulation of endopeptidase activity Database 0
Category members GO Category GO:0004866 endopeptidase inhibitor activity Database 0


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