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Query: SPECC1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SPECC1 0 0.976 0.240 -0.280

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SPECC1 Phosphorylation S54 0.281 0.655 _RAS(ph)SEDTLNKPGSTAASGVVR_
SPECC1 Phosphorylation S55 0.321 0.326 _ASS(ph)EDTLNKPGSTAASGVVR_
SPECC1 Phosphorylation S914 -0.846 -0.487 _KSPS(ph)LESLSRPPSLGFGDTR_
SPECC1 Phosphorylation S810 -0.735 -0.510 _TS(ph)PTPPESATTVK_
SPECC1 Phosphorylation T809 -0.605 _T(ph)SPTPPESATTVK_
SPECC1 Phosphorylation S131 -0.698 -0.930 _S(ph)VSSPTSSNTPTPTK_
SPECC1 Phosphorylation S912 -1.044 _KS(ph)PSLESLSRPPSLGFGDTR_

Background Information for SPECC1:


Pubmed-SPECC1 »
Uniprot-SPECC1 »
Biogrid-SPECC1 »
ProteomicsDB-SPECC1 »

Tumorportal-SPECC1 »
COSMIC-SPECC1 »
GenomeRNAi-SPECC1 »
Genecards-SPECC1


Protein-protein Interactions for SPECC1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ACTB Cat. description Hein, Mann, Cell 2015
Category members IP bait ACTR2 Cat. description Hein, Mann, Cell 2015
Category members IP bait ANLN Cat. description Hein, Mann, Cell 2015
Category members IP bait ATP6AP2 Cat. description Hein, Mann, Cell 2015
Category members IP bait CALML3 Cat. description Hein, Mann, Cell 2015
Category members IP bait CAPZA2 Cat. description Hein, Mann, Cell 2015
Category members IP bait CORO1C Cat. description Hein, Mann, Cell 2015
Category members IP bait DBN1 Cat. description Hein, Mann, Cell 2015
Category members IP bait FLNA Cat. description Hein, Mann, Cell 2015
Category members IP bait FLNB Cat. description Hein, Mann, Cell 2015
Category members IP bait FLOT2 Cat. description Hein, Mann, Cell 2015
Category members IP bait IQGAP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait ITGA5 Cat. description Hein, Mann, Cell 2015
Category members IP bait LIMA1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MAPRE1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYH10 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYH9 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO18A Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO19 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO1C Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO5C Cat. description Hein, Mann, Cell 2015
Category members IP bait PPP1CB Cat. description Hein, Mann, Cell 2015
Category members IP bait RAB5A Cat. description Hein, Mann, Cell 2015
Category members IP bait SEPT9 Cat. description Hein, Mann, Cell 2015
Category members IP bait SYNPO Cat. description Hein, Mann, Cell 2015
Category members IP bait TMOD3 Cat. description Hein, Mann, Cell 2015
Category members IP bait TPM1 Cat. description Hein, Mann, Cell 2015
Category members IP bait TPM4 Cat. description Hein, Mann, Cell 2015
Category members IP bait PCDHB11 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PCDHGB1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RAB11FIP4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLC25A41 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in SPECC1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members CH-domain IPR001715 0.63
Category members CAMSAP_CH IPR022613 0.13


Protein complexes (CORUM database) featuring SPECC1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring SPECC1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0007155 cell adhesion Database 0


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