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Query: SPC24

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SPC24 0 -0.554 0.340 -0.210

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SPC24 Ubiquitylation K50 0.122 -0.676 _LLETQDGAEK(gl)QLR_

Background Information for SPC24:


Pubmed-SPC24 »
Uniprot-SPC24 »
Biogrid-SPC24 »
ProteomicsDB-SPC24 »

Tumorportal-SPC24 »
COSMIC-SPC24 »
GenomeRNAi-SPC24 »
Genecards-SPC24


Protein-protein Interactions for SPC24
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait C20orf172;DSN1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CASC5 Cat. description Hein, Mann, Cell 2015
Category members IP bait MIS12 Cat. description Hein, Mann, Cell 2015
Category members IP bait NUF2 Cat. description Hein, Mann, Cell 2015
Category members IP bait SPC24 Cat. description Hein, Mann, Cell 2015
Category members IP bait ZWINT Cat. description Hein, Mann, Cell 2015
Category members IP bait C6orf141 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DSN1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EMILIN1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM170A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KIF2B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MLF1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NSL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PMF1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TALDO1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZWINT Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in SPC24
Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring SPC24
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 127 NDC80 kinetochore complex Database 0


Categories featuring SPC24
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members Pathway Pathway_320 REACTOME_CELL_CYCLE 0 11.08
Category members GO Category GO:0000278 mitotic cell cycle Database 10.63
Category members Pathway Pathway_321 REACTOME_MITOTIC_M_M_G1_PHASES 0 5.47
Category members Pathway Pathway_323 REACTOME_DNA_REPLICATION 0 5.24
Category members Pathway Pathway_317 REACTOME_CELL_CYCLE_MITOTIC 0 4.82
Category members Pathway Pathway_726 REACTOME_MITOTIC_PROMETAPHASE 0 2.41
Category members GO Category GO:0007067 mitosis Database 2.23
Category members GO Category GO:0000777 condensed chromosome kinetochore Database 0.32
Category members Pathway Pathway_1028 PID_PLK1_PATHWAY 0 0.16
Category members GO Category GO:0031262 Ndc80 complex Database 0


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