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Query: SPAG1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SPAG1 1 0.286 2.380 -0.810

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SPAG1 Phosphorylation S418 0.618 _GQTPEAGADKRS(ph)PR_
SPAG1 Phosphorylation S423 -0.332 -0.586 _RAS(ph)AAAAAGGGATGHPGGGQGAENPAGLK_

Background Information for SPAG1:


Pubmed-SPAG1 »
Uniprot-SPAG1 »
Biogrid-SPAG1 »
ProteomicsDB-SPAG1 »

Tumorportal-SPAG1 »
COSMIC-SPAG1 »
GenomeRNAi-SPAG1 »
Genecards-SPAG1


Protein-protein Interactions for SPAG1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ATL3 Cat. description Hein, Mann, Cell 2015
Category members IP bait CEP152 Cat. description Hein, Mann, Cell 2015
Category members IP bait COBLL1 Cat. description Hein, Mann, Cell 2015
Category members IP bait EEF1A1;EEF1A1P5 Cat. description Hein, Mann, Cell 2015
Category members IP bait LDHD Cat. description Hein, Mann, Cell 2015
Category members IP bait MIS12 Cat. description Hein, Mann, Cell 2015
Category members IP bait VPS25 Cat. description Hein, Mann, Cell 2015
Category members IP bait MAGEA1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in SPAG1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members TPR_1 IPR001440 1.39
Category members TPR-contain_dom IPR013026 0.97
Category members TPR_repeat IPR019734 0.93
Category members TPR_2 IPR013105 0.45


Protein complexes (CORUM database) featuring SPAG1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring SPAG1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0016787 hydrolase activity Database 0.22
Category members GO Category GO:0005525 GTP binding Database 0.16
Category members Disease phenotype Primary_ciliary_dyskinesia Primary ciliary dyskinesia Database 0
Category members GO Category GO:0007338 single fertilization Database 0


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