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Query: SON

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SON 0 2.120 -0.056 0.019
SON 0 2.120 -0.335 0.412 -0.263 -0.376 -0.069

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SON Ubiquitylation K16 -0.031 0.781 _SFVVSK(gl)FR_
SON Phosphorylation T1555 0.646 0.731 _EM(ox)EHNTVCAAGT(ph)SPVGEIGEEK_
SON Phosphorylation S1697 0.667 0.629 _ESDQTLAALLS(ph)PK_
SON Phosphorylation S1556 0.650 0.527 _EMEHNTVCAAGTS(ph)PVGEIGEEK_
SON Phosphorylation S283 0.075 -0.167 _SVESTS(ph)PEPSK_
SON Phosphorylation S182 -0.694 _AFGPSETNES(ph)PAVVLEPPVVSMEVSEPHILETLKPATK_
SON Phosphorylation S1769 -0.468 -0.797 _SAAS(ph)PVVSSMPER_
SON Ubiquitylation K84 -0.250 _YKPDLK(gl)EGSR_
SON Phosphorylation T1691 0.862 _ESDQT(ph)LAALLSPK_
SON Phosphorylation S1783 -0.169 _ASESS(ph)SEEKDDYEIFVK_
SON Ubiquitylation K2344 -0.264 _K(gl)GLVAVGER_

Background Information for SON:


Pubmed-SON »
Uniprot-SON »
Biogrid-SON »
ProteomicsDB-SON »

Tumorportal-SON »
COSMIC-SON »
GenomeRNAi-SON »
Genecards-SON


Protein-protein Interactions for SON
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait KIFAP3 Cat. description Hein, Mann, Cell 2015


Protein Domains in SON
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members WD40_repeat_dom IPR017986 1.39
Category members dsRNA-bd_dom IPR014720 0.23
Category members G_patch_dom IPR000467 0.09


Protein complexes (CORUM database) featuring SON
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring SON
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0003723 RNA binding Database INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0008380 RNA splicing Database 10.77
Category members GO Category GO:0016607 nuclear speck Database 4.84
Category members GO Category GO:0006397 mRNA processing Database 3.76
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0003676 nucleic acid binding Database 0.83
Category members GO Category GO:0043066 negative regulation of apoptotic process Database 0.6
Category members GO Category GO:0050733 RS domain binding Database 0.58
Category members GO Category GO:0000226 microtubule cytoskeleton organization Database 0.5
Category members GO Category GO:0000910 cytokinesis Database 0.15
Category members GO Category GO:0051726 regulation of cell cycle Database 0.11
Category members GO Category GO:0043484 regulation of RNA splicing Database 0


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