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Query: SMPD4

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SMPD4 0 -2.455 -0.820 0.770 -0.386
SMPD4 0 -2.455 -0.820 0.770 0.160 -0.145
SMPD4 0 -2.455 0.310 -0.590 -0.386
SMPD4 0 -2.455 0.310 -0.590 0.160 -0.145

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SMPD4 Phosphorylation S792 -0.397 0.128 _HLLS(ph)PVGR_
SMPD4 Phosphorylation S169 -0.702 -0.315 _ASIQECILPDS(ph)PLYHNK_
SMPD4 Ubiquitylation K453 -1.177 -1.794 _YAPDK(gl)QAPGSDSQPR_

Background Information for SMPD4:


Pubmed-SMPD4 »
Uniprot-SMPD4 »
Biogrid-SMPD4 »
ProteomicsDB-SMPD4 »

Tumorportal-SMPD4 »
COSMIC-SMPD4 »
GenomeRNAi-SMPD4 »
Genecards-SMPD4


Protein-protein Interactions for SMPD4
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait KPNB1 Cat. description Hein, Mann, Cell 2015
Category members IP bait NUP107 Cat. description Hein, Mann, Cell 2015
Category members IP bait NUP153 Cat. description Hein, Mann, Cell 2015
Category members IP bait NUP98 Cat. description Hein, Mann, Cell 2015
Category members IP bait UBE2I Cat. description Hein, Mann, Cell 2015


Protein Domains in SMPD4
Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring SMPD4
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring SMPD4
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0005789 endoplasmic reticulum membrane Database 1.57
Category members GO Category GO:0005783 endoplasmic reticulum Database 0.62
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members GO Category GO:0005794 Golgi apparatus Database 0.27
Category members GO Category GO:0005802 trans-Golgi network Database 0.13
Category members GO Category GO:0006685 sphingomyelin catabolic process Database 0.13
Category members GO Category GO:0004767 sphingomyelin phosphodiesterase activity Database 0.04
Category members GO Category GO:0071356 cellular response to tumor necrosis factor Database 0.03
Category members Pathway Pathway_100 REACTOME_PHOSPHOLIPID_METABOLISM 0 0
Category members Pathway Pathway_126 REACTOME_GLYCOSPHINGOLIPID_METABOLISM 0 0
Category members Pathway Pathway_127 KEGG_SPHINGOLIPID_METABOLISM 0 0
Category members Pathway Pathway_128 REACTOME_SPHINGOLIPID_METABOLISM 0 0
Category members Pathway Pathway_4 REACTOME_METABOLISM_OF_LIPIDS_AND_LIPOPROTEINS 0 0
Category members GO Category GO:0000139 Golgi membrane Database 0
Category members GO Category GO:0006665 sphingolipid metabolic process Database 0
Category members GO Category GO:0006687 glycosphingolipid metabolic process Database 0
Category members GO Category GO:0046475 glycerophospholipid catabolic process Database 0
Category members GO Category GO:0046513 ceramide biosynthetic process Database 0
Category members GO Category GO:0046872 metal ion binding Database 0


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