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Query: SMG8

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SMG8 0 -0.068 -0.440 0.230

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SMG8 Phosphorylation S667 -0.298 _NES(ph)SPAPPDSDADKLK_
SMG8 Phosphorylation S668 -0.298 _NES(ph)SPAPPDSDADKLK_

Background Information for SMG8:





Protein-protein Interactions for SMG8

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait SMG9 Cat. description Hein, Mann, Cell 2015


Protein Domains in SMG8

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Smg8/Smg9 IPR019354 0


Protein complexes (CORUM database) featuring SMG8

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring SMG8

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Pathway Pathway_770 REACTOME_NONSENSE_MEDIATED_DECAY_ENHANCED_BY_THE_EXON_JUNCTION_COMPLEX 0 INF
Category members Pathway Pathway_771 REACTOME_METABOLISM_OF_RNA 0 INF
Category members Pathway Pathway_773 REACTOME_METABOLISM_OF_MRNA 0 INF
Category members GO Category GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay Database INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0010467 gene expression Database INF
Category members GO Category GO:0016070 RNA metabolic process Database INF
Category members GO Category GO:0016071 mRNA metabolic process Database INF
Category members GO Category GO:0045859 regulation of protein kinase activity Database 0.01
Category members GO Category GO:0005575 cellular_component Database 0


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