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Query: SMG7

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SMG7 0 -0.852 0.060 -0.090

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SMG7 Phosphorylation S735 -0.318 -0.255 _AVPALGKS(ph)PPHHSGFQQYQQADASK_
SMG7 Ubiquitylation K77 -0.419 _NQITTLQGQAK(gl)NR_
SMG7 Phosphorylation S740 -0.178 -0.612 _AVPALGKSPPHHS(ph)GFQQYQQADASK_

Background Information for SMG7:


Pubmed-SMG7 »
Uniprot-SMG7 »
Biogrid-SMG7 »
ProteomicsDB-SMG7 »

Tumorportal-SMG7 »
COSMIC-SMG7 »
GenomeRNAi-SMG7 »
Genecards-SMG7


Protein-protein Interactions for SMG7
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait SEC16A Cat. description Hein, Mann, Cell 2015
Category members IP bait C6orf141 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CDC16 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CRYL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DNA2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KLK15 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NPAS1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TSNAX Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in SMG7
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members EST1 IPR019458 0.18


Protein complexes (CORUM database) featuring SMG7
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring SMG7
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Pathway Pathway_770 REACTOME_NONSENSE_MEDIATED_DECAY_ENHANCED_BY_THE_EXON_JUNCTION_COMPLEX 0 INF
Category members Pathway Pathway_771 REACTOME_METABOLISM_OF_RNA 0 INF
Category members Pathway Pathway_773 REACTOME_METABOLISM_OF_MRNA 0 INF
Category members GO Category GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay Database INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0010467 gene expression Database INF
Category members GO Category GO:0016070 RNA metabolic process Database INF
Category members GO Category GO:0016071 mRNA metabolic process Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0006406 mRNA export from nucleus Database 4.09
Category members GO Category GO:0045111 intermediate filament cytoskeleton Database 0.26
Category members GO Category GO:0035303 regulation of dephosphorylation Database 0.18
Category members GO Category GO:0051721 protein phosphatase 2A binding Database 0


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