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Query: SLTM

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SLTM 1 2.919 1.080 -0.810 1.559 -0.432 -0.338 0.787 0.343

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SLTM Phosphorylation S289 0.461 0.539 _DGQDAIAQS(ph)PEKESK_
SLTM Phosphorylation S551 0.442 _ISS(ph)KSPGHMVILDQTK_
SLTM Phosphorylation S553 0.402 0.183 _S(ph)PGHMVILDQTK_
SLTM Phosphorylation S1002 0.003 -0.730 _AGAGMITQHSSNAS(ph)PINR_
SLTM Phosphorylation S999 -0.104 _AGAGMITQHSS(ph)NASPINR_

Background Information for SLTM:


Pubmed-SLTM »
Uniprot-SLTM »
Biogrid-SLTM »
ProteomicsDB-SLTM »

Tumorportal-SLTM »
COSMIC-SLTM »
GenomeRNAi-SLTM »
Genecards-SLTM


Protein-protein Interactions for SLTM
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait FUS Cat. description Hein, Mann, Cell 2015
Category members IP bait MATR3 Cat. description Hein, Mann, Cell 2015
Category members IP bait SRSF1 Cat. description Hein, Mann, Cell 2015
Category members IP bait TAF15 Cat. description Hein, Mann, Cell 2015
Category members IP bait APOBEC3D Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FGL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GGPS1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GHITM Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ID2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IKZF5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LTBR Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNRNP70 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SSSCA1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZC3H18 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in SLTM
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members RRM_dom IPR000504 4.34
Category members SAP_dom IPR003034 1.96


Protein complexes (CORUM database) featuring SLTM
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring SLTM
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0003723 RNA binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members DDR Literature pubmedid:TBD1_UV_decreased Elia et al, 2015 UV decreased acetylation events Elia et al. 10.54
Category members GO Category GO:0000166 nucleotide binding Database 5.91
Category members GO Category GO:0006915 apoptotic process Database 2.12
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0003676 nucleic acid binding Database 0.83
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0


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