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Query: SLC7A5

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SLC7A5 1 5.280 -2.130 3.080 0.562 0.083 0.097

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SLC7A5 Ubiquitylation K25 0.755 0.703 _EK(gl)MLAAK_
SLC7A5 Ubiquitylation K30 0.580 0.198 _MLAAK(gl)SADGSAPAGEGEGVTLQR_
SLC7A5 Ubiquitylation K19 0.118 0.019 _ALAAPAAEEK(gl)EEAR_

Background Information for SLC7A5:


Pubmed-SLC7A5 »
Uniprot-SLC7A5 »
Biogrid-SLC7A5 »
ProteomicsDB-SLC7A5 »

Tumorportal-SLC7A5 »
COSMIC-SLC7A5 »
GenomeRNAi-SLC7A5 »
Genecards-SLC7A5


Protein-protein Interactions for SLC7A5
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait MBOAT1 Cat. description Hein, Mann, Cell 2015
Category members IP bait NCSTN Cat. description Hein, Mann, Cell 2015
Category members IP bait SMN1 Cat. description Hein, Mann, Cell 2015
Category members IP bait TMED2 Cat. description Hein, Mann, Cell 2015
Category members IP bait TMEM63B Cat. description Hein, Mann, Cell 2015
Category members IP bait TUBA1C Cat. description Hein, Mann, Cell 2015


Protein Domains in SLC7A5
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members AA-permease/SLC12A_dom IPR004841 0.08
Category members AA/rel_permease1 IPR002293 0
Category members L_AA_transporter IPR004760 0


Protein complexes (CORUM database) featuring SLC7A5
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring SLC7A5
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0016020 membrane Database 0.52
Category members Pathway Pathway_53 REACTOME_HEMOSTASIS 0 0.4
Category members GO Category GO:0007596 blood coagulation Database 0.4
Category members GO Category GO:0015179 L-amino acid transmembrane transporter activity Database 0.35
Category members GO Category GO:0015807 L-amino acid transport Database 0.35
Category members Pathway Pathway_1307 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE 0 0.32
Category members Pathway Pathway_96 REACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT 0 0.23
Category members GO Category GO:0006811 ion transport Database 0.18
Category members GO Category GO:0055085 transmembrane transport Database 0.12
Category members Pathway Pathway_1271 REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS 0 0.11
Category members Pathway Pathway_99 REACTOME_TRANSMEMBRANE_TRANSPORT_OF_SMALL_MOLECULES 0 0.08
Category members GO Category GO:0030154 cell differentiation Database 0.06
Category members Pathway Pathway_600 REACTOME_CELL_SURFACE_INTERACTIONS_AT_THE_VASCULAR_WALL 0 0.05
Category members GO Category GO:0050900 leukocyte migration Database 0.04
Category members GO Category GO:0015804 neutral amino acid transport Database 0.03
Category members GO Category GO:0015175 neutral amino acid transmembrane transporter activity Database 0.02
Category members Pathway Pathway_927 REACTOME_BASIGIN_INTERACTIONS 0 0
Category members Pathway Pathway_1207 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES 0 0
Category members GO Category GO:0003333 amino acid transmembrane transport Database 0
Category members GO Category GO:0006520 cellular amino acid metabolic process Database 0
Category members GO Category GO:0006810 transport Database 0
Category members GO Category GO:0006865 amino acid transport Database 0
Category members GO Category GO:0007399 nervous system development Database 0
Category members GO Category GO:0015171 amino acid transmembrane transporter activity Database 0
Category members GO Category GO:0016324 apical plasma membrane Database 0
Category members GO Category GO:0042605 peptide antigen binding Database 0


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