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Query: SLC7A2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SLC7A2 0 3.935 1.330 -0.900
SLC7A2 0 3.935 1.330 -0.900 1.122 0.799

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SLC7A2 Ubiquitylation K29 1.076 0.938 _IVTLDSLEDTK(gl)LCR_
SLC7A2 Ubiquitylation K461 1.011 0.868 _VTSK(gl)SESQVTMLQR_
SLC7A2 Ubiquitylation K383 0.272 _CLAQINSK(gl)TK_
SLC7A2 Ubiquitylation K654 0.472 -0.114 _NLSSPFIFHEK(gl)TSEF_
SLC7A2 Ubiquitylation K629 0.653 -0.138 _TPDGNLDQCK(gl)_
SLC7A2 Ubiquitylation K449 0.152 -0.687 _CSPEK(gl)DGLGSSPR_

Background Information for SLC7A2:


Pubmed-SLC7A2 »
Uniprot-SLC7A2 »
Biogrid-SLC7A2 »
ProteomicsDB-SLC7A2 »

Tumorportal-SLC7A2 »
COSMIC-SLC7A2 »
GenomeRNAi-SLC7A2 »
Genecards-SLC7A2


Protein-protein Interactions for SLC7A2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ATP6V0E1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C3AR1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CD83 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CYP2C18 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DLK2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FPR2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GABRE Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GPR77 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LGALS3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MFSD4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NT5E Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PTGIR Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMPRSS11B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TSPAN5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait UPK1A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VAPB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VIPR1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VSIG4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait YIPF3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZFYVE27 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in SLC7A2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Cat_AA_permease IPR004755 0.57
Category members AA-permease/SLC12A_dom IPR004841 0.08
Category members AA/rel_permease1 IPR002293 0


Protein complexes (CORUM database) featuring SLC7A2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring SLC7A2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0005887 integral to plasma membrane Database 1.69
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0015181 arginine transmembrane transporter activity Database 0.79
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0015189 L-lysine transmembrane transporter activity Database 0.43
Category members GO Category GO:0015819 lysine transport Database 0.43
Category members GO Category GO:0015809 arginine transport Database 0.38
Category members GO Category GO:0015179 L-amino acid transmembrane transporter activity Database 0.35
Category members GO Category GO:0015807 L-amino acid transport Database 0.35
Category members Pathway Pathway_1307 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE 0 0.32
Category members Pathway Pathway_96 REACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT 0 0.23
Category members GO Category GO:0006811 ion transport Database 0.18
Category members GO Category GO:0055085 transmembrane transport Database 0.12
Category members Pathway Pathway_1271 REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS 0 0.11
Category members Pathway Pathway_99 REACTOME_TRANSMEMBRANE_TRANSPORT_OF_SMALL_MOLECULES 0 0.08
Category members Pathway Pathway_1207 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES 0 0
Category members GO Category GO:0000064 L-ornithine transmembrane transporter activity Database 0
Category members GO Category GO:0002537 nitric oxide production involved in inflammatory response Database 0
Category members GO Category GO:0003333 amino acid transmembrane transport Database 0
Category members GO Category GO:0006520 cellular amino acid metabolic process Database 0
Category members GO Category GO:0006809 nitric oxide biosynthetic process Database 0
Category members GO Category GO:0006810 transport Database 0
Category members GO Category GO:0006865 amino acid transport Database 0
Category members GO Category GO:0015171 amino acid transmembrane transporter activity Database 0
Category members GO Category GO:0015174 basic amino acid transmembrane transporter activity Database 0
Category members GO Category GO:0042116 macrophage activation Database 0
Category members GO Category GO:0043030 regulation of macrophage activation Database 0
Category members GO Category GO:0050727 regulation of inflammatory response Database 0


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