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Query: SLC6A6

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SLC6A6 1 2.798 0.890 -0.980

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SLC6A6 Ubiquitylation K11 1.952 0.702 _LQCLK(gl)DFHK_
SLC6A6 Ubiquitylation K6 2.097 0.595 _EK(gl)LQCLK_
SLC6A6 Ubiquitylation K4 2.097 -0.472 _(ac)ATK(gl)EK(gl)LQCLK_
SLC6A6 Ubiquitylation K19 0.313 -0.579 _DILK(gl)PSPGK_
SLC6A6 Ubiquitylation K577 -0.987 _VK(gl)YLLTPR_
SLC6A6 Ubiquitylation K15 0.867 _DFHK(gl)DILKPSPGK_

Background Information for SLC6A6:


Pubmed-SLC6A6 »
Uniprot-SLC6A6 »
Biogrid-SLC6A6 »
ProteomicsDB-SLC6A6 »

Tumorportal-SLC6A6 »
COSMIC-SLC6A6 »
GenomeRNAi-SLC6A6 »
Genecards-SLC6A6


Protein-protein Interactions for SLC6A6
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait GPR114 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GPR21 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LGALS9 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NMUR2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PDZK1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in SLC6A6
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Na/ntran_symport IPR000175 0


Protein complexes (CORUM database) featuring SLC6A6
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring SLC6A6
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0005887 integral to plasma membrane Database 1.69
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members Pathway Pathway_1307 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE 0 0.32
Category members Pathway Pathway_96 REACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT 0 0.23
Category members GO Category GO:0006811 ion transport Database 0.18
Category members GO Category GO:0055085 transmembrane transport Database 0.12
Category members Pathway Pathway_1271 REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS 0 0.11
Category members Pathway Pathway_99 REACTOME_TRANSMEMBRANE_TRANSPORT_OF_SMALL_MOLECULES 0 0.08
Category members Pathway Pathway_1308 REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS 0 0.05
Category members Pathway Pathway_1207 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES 0 0
Category members Pathway Pathway_1309 REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS 0 0
Category members Pathway Pathway_750 REACTOME_TRANSPORT_OF_GLUCOSE_AND_OTHER_SUGARS_BILE_SALTS_AND_ORGANIC_ACIDS_METAL_IONS_AND_AMINE_COMPOUNDS 0 0
Category members GO Category GO:0005328 neurotransmitter:sodium symporter activity Database 0
Category members GO Category GO:0006520 cellular amino acid metabolic process Database 0
Category members GO Category GO:0006810 transport Database 0
Category members GO Category GO:0006836 neurotransmitter transport Database 0
Category members GO Category GO:0006865 amino acid transport Database 0
Category members GO Category GO:0030977 taurine binding Database 0


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