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Query: SLC6A11

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SLC6A11 1 3.708 0.230 0.110

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SLC6A11 Ubiquitylation K628 1.312 1.394 _SDGTIAAITEK(gl)ETHF_
SLC6A11 Ubiquitylation K13 1.336 1.292 _ALPLGNGK(gl)AAEEAR_
SLC6A11 Ubiquitylation K617 1.199 _MVTVNDCDAKLK(gl)_
SLC6A11 Ubiquitylation K615 2.313 _MVTVNDCDAK(gl)LK_

Background Information for SLC6A11:


Pubmed-SLC6A11 »
Uniprot-SLC6A11 »
Biogrid-SLC6A11 »
ProteomicsDB-SLC6A11 »

Tumorportal-SLC6A11 »
COSMIC-SLC6A11 »
GenomeRNAi-SLC6A11 »
Genecards-SLC6A11


Protein-protein Interactions for SLC6A11
Show screen data for Category Name and Description Link to cat description Data Source


Protein Domains in SLC6A11
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Na/ntran_symport IPR000175 0
Category members S-AdoMet_deCO2ase_core IPR016067 0


Protein complexes (CORUM database) featuring SLC6A11
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring SLC6A11
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0005887 integral to plasma membrane Database 1.69
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0042493 response to drug Database 0.66
Category members GO Category GO:0016020 membrane Database 0.52
Category members Pathway Pathway_96 REACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT 0 0.23
Category members GO Category GO:0007268 synaptic transmission Database 0.23
Category members GO Category GO:0055085 transmembrane transport Database 0.12
Category members Pathway Pathway_99 REACTOME_TRANSMEMBRANE_TRANSPORT_OF_SMALL_MOLECULES 0 0.08
Category members GO Category GO:0042165 neurotransmitter binding Database 0.08
Category members Pathway Pathway_1308 REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS 0 0.05
Category members Pathway Pathway_389 REACTOME_GABA_SYNTHESIS_RELEASE_REUPTAKE_AND_DEGRADATION 0 0.04
Category members Pathway Pathway_1309 REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS 0 0
Category members Pathway Pathway_139 REACTOME_NEURONAL_SYSTEM 0 0
Category members Pathway Pathway_140 REACTOME_TRANSMISSION_ACROSS_CHEMICAL_SYNAPSES 0 0
Category members Pathway Pathway_390 REACTOME_NEUROTRANSMITTER_RELEASE_CYCLE 0 0
Category members Pathway Pathway_750 REACTOME_TRANSPORT_OF_GLUCOSE_AND_OTHER_SUGARS_BILE_SALTS_AND_ORGANIC_ACIDS_METAL_IONS_AND_AMINE_COMPOUNDS 0 0
Category members GO Category GO:0004014 adenosylmethionine decarboxylase activity Database 0
Category members GO Category GO:0005328 neurotransmitter:sodium symporter activity Database 0
Category members GO Category GO:0005332 gamma-aminobutyric acid:sodium symporter activity Database 0
Category members GO Category GO:0006836 neurotransmitter transport Database 0
Category members GO Category GO:0007269 neurotransmitter secretion Database 0
Category members GO Category GO:0007420 brain development Database 0
Category members GO Category GO:0008295 spermidine biosynthetic process Database 0
Category members GO Category GO:0042995 cell projection Database 0


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