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Query: SLC22A5

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SLC22A5 0 2.622 -0.260 0.470

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SLC22A5 Ubiquitylation K553 1.056 1.095 _DGQERPTILK(gl)STAF_
SLC22A5 Ubiquitylation K543 0.422 -0.026 _MLK(gl)DGQERPTILK_

Background Information for SLC22A5:


Pubmed-SLC22A5 »
Uniprot-SLC22A5 »
Biogrid-SLC22A5 »
ProteomicsDB-SLC22A5 »

Tumorportal-SLC22A5 »
COSMIC-SLC22A5 »
GenomeRNAi-SLC22A5 »
Genecards-SLC22A5


Protein-protein Interactions for SLC22A5
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait PDZK1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLC22A5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLC22A9 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait YIPF3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in SLC22A5
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Orgcat_transp IPR004749 0
Category members Sub_transporter IPR005828 0
Category members MFS IPR011701 0
Category members MFS_dom_general_subst_transpt IPR016196 0
Category members MFS_dom IPR020846 0


Protein complexes (CORUM database) featuring SLC22A5
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring SLC22A5
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0030165 PDZ domain binding Database 0.29
Category members Pathway Pathway_96 REACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT 0 0.23
Category members GO Category GO:0055085 transmembrane transport Database 0.12
Category members GO Category GO:0006814 sodium ion transport Database 0.09
Category members Pathway Pathway_99 REACTOME_TRANSMEMBRANE_TRANSPORT_OF_SMALL_MOLECULES 0 0.08
Category members GO Category GO:0016323 basolateral plasma membrane Database 0.04
Category members GO Category GO:0015651 quaternary ammonium group transmembrane transporter activity Database 0.01
Category members GO Category GO:0015697 quaternary ammonium group transport Database 0.01
Category members Pathway Pathway_1317 REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT 0 0
Category members Pathway Pathway_750 REACTOME_TRANSPORT_OF_GLUCOSE_AND_OTHER_SUGARS_BILE_SALTS_AND_ORGANIC_ACIDS_METAL_IONS_AND_AMINE_COMPOUNDS 0 0
Category members GO Category GO:0006855 drug transmembrane transport Database 0
Category members GO Category GO:0015075 ion transmembrane transporter activity Database 0
Category members GO Category GO:0015226 carnitine transmembrane transporter activity Database 0
Category members GO Category GO:0015238 drug transmembrane transporter activity Database 0
Category members GO Category GO:0015293 symporter activity Database 0
Category members GO Category GO:0015879 carnitine transport Database 0
Category members GO Category GO:0015893 drug transport Database 0
Category members GO Category GO:0016324 apical plasma membrane Database 0
Category members GO Category GO:0022857 transmembrane transporter activity Database 0
Category members GO Category GO:0031526 brush border membrane Database 0
Category members GO Category GO:0034220 ion transmembrane transport Database 0
Category members GO Category GO:0042891 antibiotic transport Database 0
Category members GO Category GO:0042895 antibiotic transporter activity Database 0


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