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Query: SLC22A18

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SLC22A18 0 -1.668 0.610 -0.440

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SLC22A18 Ubiquitylation K210 -1.668 _GAK(gl)TDAQAPLPGGPR_

Background Information for SLC22A18:





Protein-protein Interactions for SLC22A18

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait AMIGO3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C3AR1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CA14 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CHST10 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CLEC2D Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GYPA Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HAVCR2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HLA-DPA1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HLA-DQA1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ITM2A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KITLG Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LAMP3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MME Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MRAP2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NRG1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PMEL Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SGK196 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLC39A12 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLC39A4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLC39A5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLC39A8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLC7A1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SPACA1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TXNDC15 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VSIG1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in SLC22A18

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Tet-R_TetA/multi-R_MdtG IPR001958 0
Category members MFS IPR011701 0
Category members MFS_dom_general_subst_transpt IPR016196 0
Category members MFS_dom IPR020846 0


Protein complexes (CORUM database) featuring SLC22A18

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring SLC22A18

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0005635 nuclear envelope Database 7.22
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0031625 ubiquitin protein ligase binding Database 2.54
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members Disease phenotype BREAST_CANCER BREAST CANCER Database 0.62
Category members Pathway Pathway_96 REACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT 0 0.23
Category members GO Category GO:0055085 transmembrane transport Database 0.12
Category members Disease phenotype LUNG_CANCER LUNG CANCER Database 0.12
Category members Pathway Pathway_99 REACTOME_TRANSMEMBRANE_TRANSPORT_OF_SMALL_MOLECULES 0 0.08
Category members GO Category GO:0007588 excretion Database 0.08
Category members Pathway Pathway_1317 REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT 0 0
Category members Pathway Pathway_750 REACTOME_TRANSPORT_OF_GLUCOSE_AND_OTHER_SUGARS_BILE_SALTS_AND_ORGANIC_ACIDS_METAL_IONS_AND_AMINE_COMPOUNDS 0 0
Category members GO Category GO:0005215 transporter activity Database 0
Category members GO Category GO:0006855 drug transmembrane transport Database 0
Category members GO Category GO:0015238 drug transmembrane transporter activity Database 0
Category members GO Category GO:0015293 symporter activity Database 0
Category members GO Category GO:0015695 organic cation transport Database 0
Category members GO Category GO:0015893 drug transport Database 0
Category members GO Category GO:0016324 apical plasma membrane Database 0


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